Drug targeting through platelet membrane-coated nanoparticles for the treatment of rheumatoid arthritis
Sign Up to like & getrecommendations! Published in 2018 at "Nano Research"
DOI: 10.1007/s12274-018-2126-5
Abstract: The effective drug treatment of rheumatoid arthritis (RA) is hindered by poor delivery efficiency to the diseased site and the serious side effects caused by wide-spread drug distribution. Traditional drug-targeting strategies, such as ligand modification,… read more here.
Keywords: drug; treatment rheumatoid; rheumatoid arthritis; drug targeting ... See more keywords
An injectable, electrostatically interacting drug depot for the treatment of rheumatoid arthritis.
Sign Up to like & getrecommendations! Published in 2018 at "Biomaterials"
DOI: 10.1016/j.biomaterials.2017.10.055
Abstract: To the best of our knowledge, no studies have yet examined the electrostatic interaction of polyelectrolytes with electrolyte drugs for the treatment of rheumatoid arthritis (RA). Here, an injectable, electrostatically interacting drug depot is described.… read more here.
Keywords: interacting drug; depot; electrostatically interacting; treatment rheumatoid ... See more keywords
Targeting CD34+ cells of the inflamed synovial endothelium by guided nanoparticles for the treatment of rheumatoid arthritis.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of autoimmunity"
DOI: 10.1016/j.jaut.2019.05.016
Abstract: Despite the advances in the treatment of rheumatoid arthritis (RA) achieved in the last few years, several patients are diagnosed late, do not respond to or have to stop therapy because of inefficacy and/or toxicity,… read more here.
Keywords: treatment rheumatoid; arthritis; rheumatoid arthritis; cd34 endothelial ... See more keywords
Insights into the treatment of rheumatoid arthritis: A paradigm in medicine.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of autoimmunity"
DOI: 10.1016/j.jaut.2020.102425
Abstract: Insights into rheumatoid arthritis (RA) have slowly evolved over the last century, but with breathtaking speed over the last 2 decades. While only aspirin and parenteral gold were available in early 20th century, the efficacy… read more here.
Keywords: medicine; treatment rheumatoid; rheumatoid arthritis; insights treatment ... See more keywords
PMS23 - OPTIMIZING TREATMENT FOR RHEUMATOID ARTHRITIS IN THE KINGDOM OF SAUDI ARABIA (OPTRA)
Sign Up to like & getrecommendations! Published in 2018 at "Value in Health"
DOI: 10.1016/j.jval.2018.09.1737
Abstract: Almudaiheem HY1, Mohamed O2, Dawoud D3, Alsuwayeh Y1, Alenizi K4, Mughari M5, al Shubbar N6, Mekwar B1, Prasanna R2, Alasmari M1, Awad N.2. 1Ministry of Health, Riyadh, Saudi Arabia, 2IQVIA, Dubai, United Arab Emirates, 3Cairo… read more here.
Keywords: optimizing treatment; pms23 optimizing; treatment rheumatoid; saudi arabia ... See more keywords
Identification of TUL01101: A Novel Potent and Selective JAK1 Inhibitor for the Treatment of Rheumatoid Arthritis.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of medicinal chemistry"
DOI: 10.1021/acs.jmedchem.2c01550
Abstract: Janus kinase 1 (JAK1) is a potential target for the treatment of rheumatoid arthritis (RA). In this study, the introduction of a spiro ring with a difluoro-substituted cyclopropionamide resulted in the identification of TUL01101 (compound… read more here.
Keywords: treatment rheumatoid; jak1; rheumatoid arthritis; arthritis ... See more keywords
Emerging protein kinase inhibitors for the treatment of rheumatoid arthritis
Sign Up to like & getrecommendations! Published in 2021 at "Expert Opinion on Emerging Drugs"
DOI: 10.1080/14728214.2021.1964472
Abstract: ABSTRACT Introduction: Protein tyrosine kinase inhibitors are emergent drugs in the treatment of rheumatoid arthritis (RA); they block the signal transduction in immune cells preventing the production and release of pro-inflammatory cytokines. Areas covered: The… read more here.
Keywords: kinase inhibitors; kinase; treatment rheumatoid; rheumatoid arthritis ... See more keywords
Baricitinib for the treatment of rheumatoid arthritis and systemic lupus erythematosus: a 2019 update
Sign Up to like & getrecommendations! Published in 2019 at "Expert Review of Clinical Immunology"
DOI: 10.1080/1744666x.2019.1608821
Abstract: ABSTRACT Introduction: JAK, which constitutively binds to some cytokine receptors, plays an important role in cytokine signaling. While JAK is comprised of JAK1, JAK2, JAK3, and Tyk2, more than 40 types of cytokines transmit signals… read more here.
Keywords: rheumatoid arthritis; treatment rheumatoid; baricitinib treatment;
Subcutaneous injection of methotrexate: advantages in the treatment of rheumatoid arthritis.
Sign Up to like & getrecommendations! Published in 2022 at "Modern rheumatology"
DOI: 10.1093/mr/roac156
Abstract: Methotrexate is a conventional synthetic disease-modifying anti-rheumatic drug, that is used in the treatment of rheumatoid arthritis. However, insufficient responses to oral methotrexate at lower doses as well as increased variation of drug bioavailability and… read more here.
Keywords: treatment rheumatoid; subcutaneous injection; rheumatoid arthritis; methotrexate ... See more keywords
The efficacy and safety of silver needle in the treatment of rheumatoid arthritis
Sign Up to like & getrecommendations! Published in 2021 at "Medicine"
DOI: 10.1097/md.0000000000025556
Abstract: Abstract Background: Rheumatoid arthritis is a kind of chronic crippling disease, the condition is complex, the course of the disease is repeated, seriously affecting the quality of life of patients. Adverse reactions and drug resistance… read more here.
Keywords: rheumatoid arthritis; treatment; silver needle; treatment rheumatoid ... See more keywords
Mania induced by isoniazid preventive therapy during steroid treatment for rheumatoid arthritis and organising pneumonia
Sign Up to like & getrecommendations! Published in 2019 at "BMJ Case Reports"
DOI: 10.1136/bcr-2019-231919
Abstract: Isoniazid preventative therapy is widely used for latent tuberculosis infection. Isoniazid is highly effective but has many adverse effects, including neuropsychiatric. We describe the case of an 80-year-old woman with mania. She had received isoniazid… read more here.
Keywords: steroid treatment; arthritis organising; treatment rheumatoid; rheumatoid arthritis ... See more keywords