Residual Weighted Learning for Estimating Individualized Treatment Rules
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DOI: 10.1080/01621459.2015.1093947
Abstract: ABSTRACT Personalized medicine has received increasing attention among statisticians, computer scientists, and clinical practitioners. A major component of personalized medicine is the estimation of individualized treatment rules (ITRs). Recently, Zhao et al. proposed outcome weighted… read more here.
Keywords: individualized treatment; medicine; treatment rules; treatment ... See more keywords
Comment: Individualized Treatment Rules Under Endogeneity
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DOI: 10.1080/01621459.2020.1831923
Abstract: This note discusses two recent studies on identification of individualized treatment rules using instrumental variables---Cui and Tchetgen Tchetgen (2020) and Qiu et al. (2020). It also proposes identifying assumptions that are alternative to what is… read more here.
Keywords: individualized treatment; comment individualized; rules endogeneity; treatment rules ... See more keywords
Robust outcome weighted learning for optimal individualized treatment rules
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DOI: 10.1080/10543406.2019.1633657
Abstract: ABSTRACT Personalized medicine has received increasing attentions among scientific communities in recent years. Because patients often have heterogenous responses to treatments, discovering individualized treatment rules (ITR) is an important component of precision medicine. To that… read more here.
Keywords: individualized treatment; medicine; treatment rules; treatment ... See more keywords
Incorporating Patient Preferences into Estimation of Optimal Individualized Treatment Rules.
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DOI: 10.1111/biom.12743
Abstract: Precision medicine seeks to provide treatment only if, when, to whom, and at the dose it is needed. Thus, precision medicine is a vehicle by which healthcare can be made both more effective and efficient.… read more here.
Keywords: individualized treatment; medicine; optimal individualized; treatment rules ... See more keywords
Net benefit index: Assessing the influence of a biomarker for individualized treatment rules.
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DOI: 10.1111/biom.13373
Abstract: One central task in precision medicine is to establish individualized treatment rules (ITRs) for patients with heterogeneous responses to different therapies. Motivated from a randomized clinical trial for Type 2 diabetic patients on a comparison… read more here.
Keywords: individualized treatment; index; treatment rules; biomarker ... See more keywords
Estimating optimal individualized treatment rules with multistate processes.
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DOI: 10.1111/biom.13864
Abstract: Multistate process data are common in studies of chronic diseases such as cancer. These data are ideal for precision medicine purposes as they can be leveraged to improve more refined health outcomes, compared to standard… read more here.
Keywords: individualized treatment; methodology; estimating optimal; treatment rules ... See more keywords
Estimating individualized treatment rules in longitudinal studies with covariate-driven observation times.
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DOI: 10.1177/09622802231158733
Abstract: The sequential treatment decisions made by physicians to treat chronic diseases are formalized in the statistical literature as dynamic treatment regimes. To date, methods for dynamic treatment regimes have been developed under the assumption that… read more here.
Keywords: individualized treatment; observation times; dynamic treatment; treatment rules ... See more keywords