Lumateperone: First Approval
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DOI: 10.1007/s40265-020-01271-6
Abstract: Lumateperone (Caplyta ® ) is a novel, orally available agent developed by Intra-Cellular Therapies (under a license from Bristol-Myers Squibb) for the treatment of schizophrenia and other neuropsychiatric and neurological disorders. Lumateperone is a first-in-class… read more here.
Keywords: first approval; lumateperone; lumateperone first; treatment schizophrenia ... See more keywords
Roll of the Third Wave Therapies in the Treatment of Schizophrenia
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DOI: 10.1016/j.eurpsy.2017.01.1477
Abstract: Introduction The schizophrenia is a frequent mental disorder. The symptoms affect the emotions, cognition, perception and other aspects of the behaviour. In the last years have been developed different interventions and psychological treatments in order… read more here.
Keywords: schizophrenia; third wave; treatment; treatment schizophrenia ... See more keywords
Ulotaront: a TAAR1/5-HT1A agonist in clinical development for the treatment of schizophrenia
Sign Up to like & getrecommendations! Published in 2022 at "Expert Opinion on Investigational Drugs"
DOI: 10.1080/13543784.2022.2158811
Abstract: ABSTRACT Introduction Current antipsychotics are postsynaptic dopamine-2(D2) receptor blockers, which often, but not always, effectively improve acute psychotic symptoms and prevent relapse in schizophrenia and other severe mental disorders, but are associated with various side… read more here.
Keywords: treatment schizophrenia; phase trials; treatment; schizophrenia ... See more keywords
Olanzapine-samidorphan combination tablets for the treatment of schizophrenia and bipolar I disorder - what is it, and will it be used?
Sign Up to like & getrecommendations! Published in 2022 at "Expert Review of Neurotherapeutics"
DOI: 10.1080/14737175.2022.2060742
Abstract: ABSTRACT Introduction Although olanzapine remains one of the most efficacious antipsychotic medications for the treatment of schizophrenia, there are significant tolerability concerns related to its weight and metabolic profile. Olanzapine-samidorphan combination tablets (OLZ/SAM), branded as… read more here.
Keywords: olanzapine samidorphan; olz sam; olanzapine; samidorphan combination ... See more keywords
Novel multi-target ligands of dopamine and serotonin receptors for the treatment of schizophrenia based on indazole and piperazine scaffolds–synthesis, biological activity, and structural evaluation
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Enzyme Inhibition and Medicinal Chemistry"
DOI: 10.1080/14756366.2023.2209828
Abstract: Abstract Schizophrenia is a chronic mental disorder that is not satisfactorily treated with available antipsychotics. The presented study focuses on the search for new antipsychotics by optimising the compound D2AAK3, a multi-target ligand of G-protein-coupled… read more here.
Keywords: schizophrenia; multi target; treatment schizophrenia;
Psychopharmacological treatment of schizophrenia during pregnancy and lactation
Sign Up to like & getrecommendations! Published in 2017 at "Current Opinion in Psychiatry"
DOI: 10.1097/yco.0000000000000329
Abstract: Purpose of review It is necessary, in every-day clinical life when treating pregnant women with mental diseases, to reach quick decisions derived from recent comprehensive information. The knowledge of the use of antipsychotics in pregnancy… read more here.
Keywords: pregnancy; treatment schizophrenia; antipsychotics pregnancy; use antipsychotics ... See more keywords
Pyridoxamine: A novel treatment for schizophrenia with enhanced carbonyl stress
Sign Up to like & getrecommendations! Published in 2018 at "Psychiatry and Clinical Neurosciences"
DOI: 10.1111/pcn.12613
Abstract: The aim of this clinical trial was to obtain proof of concept for high‐dose pyridoxamine as a novel treatment for schizophrenia with enhanced carbonyl stress. read more here.
Keywords: novel treatment; schizophrenia enhanced; enhanced carbonyl; treatment schizophrenia ... See more keywords
Update Research Advances in the Application of Transcranial Magnetic Stimulation in the Treatment of Schizophrenia
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DOI: 10.1155/2022/5415775
Abstract: Schizophrenia presents a chronic progressive course and requires long-term treatment. The current treatment of schizophrenia is mainly based on antipsychotic drugs, but drugs are ineffective for the negative symptoms and cognitive dysfunction of schizophrenia, and… read more here.
Keywords: magnetic stimulation; treatment; transcranial magnetic; schizophrenia ... See more keywords
Physical activity as a therapeutic method for non-pharmacological treatment of schizophrenia: A systematic literature review.
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DOI: 10.12740/pp/140053
Abstract: AIM The purpose of this systematic review was to classify, compare and characterize selected types of physical activity having a positive impact on the course of the treatment of schizophrenia (including its long-term effects). MATERIAL… read more here.
Keywords: activity; literature review; physical activity; treatment schizophrenia ... See more keywords
The efficacy and safety of sodium nitroprusside in the treatment of schizophrenia: Protocol for an updated systematic review and meta-analysis
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DOI: 10.1371/journal.pone.0283185
Abstract: Background Schizophrenia is a chronic persistent disease with high recurrence rate and high disability rate in the field of psychiatry. Sodium nitroprusside is a nitric oxide (NO) donor and considered a promising new compound for… read more here.
Keywords: analysis; sodium nitroprusside; treatment schizophrenia; nitroprusside treatment ... See more keywords
Paliperidone 3-Month Injection for Treatment of Schizophrenia: A Narrative Review
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Psychiatry"
DOI: 10.3389/fpsyt.2021.699748
Abstract: Given the typical age onset of schizophrenia, there are tremendous economic and social impacts that extend beyond the person and their families. One critical determinant of the diseases' impact is the patient's adherence to antipsychotic… read more here.
Keywords: relapse; oral paliperidone; paliperidone; treatment schizophrenia ... See more keywords