Efficacy and Safety of Fenfluramine for the Treatment of Seizures Associated With Lennox-Gastaut Syndrome
Sign Up to like & getrecommendations! Published in 2022 at "JAMA Neurology"
DOI: 10.1001/jamaneurol.2022.0829
Abstract: This randomized clinical trial examines the change from baseline in drop seizure frequency, response rates, and improvement on the Clinical Global Impression scale among patients with Lennox-Gastaut syndrome. read more here.
Keywords: lennox gastaut; safety fenfluramine; fenfluramine treatment; treatment seizures ... See more keywords
Stiripentol for the treatment of seizures associated with Dravet syndrome in patients 6 months and older and taking clobazam
Sign Up to like & getrecommendations! Published in 2023 at "Expert Review of Neurotherapeutics"
DOI: 10.1080/14737175.2023.2195550
Abstract: ABSTRACT Introduction Stiripentol (STP) is a structurally unique molecule with anticonvulsant and neuroprotective properties in animal and human studies. STP enhances gamma-aminobutyric acid (GABA)ergic neurotransmission and inhibits multiple hepatic isoenzymes (i.e. cytochrome P450 system) involved… read more here.
Keywords: stiripentol treatment; treatment seizures; stp; dravet syndrome ... See more keywords
Expediting Treatment of Seizures in the Intensive Care Nursery
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DOI: 10.1542/peds.2020-013730
Abstract: OBJECTIVES Prolonged neonatal seizures are associated with poor neurodevelopmental outcomes. The aim of this quality improvement project was to decrease the time to medical treatment of seizures by 45% within 15 months for neonates admitted… read more here.
Keywords: treatment; treatment seizures; intensive care; process ... See more keywords
Pre-Treatment Seizures in Patients With 1-3 Cerebral Metastases Receiving Local Therapies Plus Whole-brain Radiotherapy
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DOI: 10.21873/invivo.12094
Abstract: Background/Aim: Seizures impair patients' quality of life. The prognostic role of pre-treatment seizures in patients with 1-3 cerebral metastases receiving local therapies plus whole-brain radiotherapy (WBRT) was investigated. Patients and Methods: In 249 patients, prevalence,… read more here.
Keywords: cerebral metastases; treatment; treatment seizures; therapies plus ... See more keywords