Four reasons why early detection centers for psychosis should be renamed and their treatment targets reconsidered: we should not catastrophize a future we can neither reliably predict nor change
Sign Up to like & getrecommendations! Published in 2019 at "Psychological Medicine"
DOI: 10.1017/s0033291719001740
Abstract: Abstract Since the 1990s, facilities for individuals at putative risk for psychosis have mushroomed and within a very short time have become part of the standard psychiatric infrastructure in many countries. The idea of preventing… read more here.
Keywords: psychosis; treatment; four reasons; renamed treatment ... See more keywords
Tumour-associated macrophages as treatment targets in oncology
Sign Up to like & getrecommendations! Published in 2017 at "Nature Reviews Clinical Oncology"
DOI: 10.1038/nrclinonc.2016.217
Abstract: Macrophages are crucial drivers of tumour-promoting inflammation. Tumour-associated macrophages (TAMs) contribute to tumour progression at different levels: by promoting genetic instability, nurturing cancer stem cells, supporting metastasis, and taming protective adaptive immunity. TAMs can exert… read more here.
Keywords: treatment targets; tumour associated; oncology tumour; macrophages treatment ... See more keywords
Main Symptomatic Treatment Targets in Suspected and Early Psychosis: New Insights From Network Analysis.
Sign Up to like & getrecommendations! Published in 2020 at "Schizophrenia bulletin"
DOI: 10.1093/schbul/sbz140
Abstract: The early detection and intervention in psychoses prior to their first episode are presently based on the symptomatic ultra-high-risk and the basic symptom criteria. Current models of symptom development assume that basic symptoms develop first,… read more here.
Keywords: treatment targets; network; symptom; network analysis ... See more keywords
Role of public-private partnerships in achieving UNAIDS HIV treatment targets
Sign Up to like & getrecommendations! Published in 2019 at "BMC Health Services Research"
DOI: 10.1186/s12913-018-3744-z
Abstract: BackgroundDespite progress towards achieving UNAIDS 90–90-90 goals, barriers persist in laboratory systems in sub-Saharan Africa (SSA) restricting scale up of early infant diagnosis (EID) and viral load (VL) test monitoring of patients on antiretroviral therapy.… read more here.
Keywords: treatment targets; public private; treatment; achieving unaids ... See more keywords
Vasoactive pharmacological management according to SCAI class in patients with acute myocardial infarction and cardiogenic shock
Sign Up to like & getrecommendations! Published in 2022 at "PLoS ONE"
DOI: 10.1371/journal.pone.0272279
Abstract: Background Vasoactive treatment is a cornerstone in treating hypoperfusion in cardiogenic shock following acute myocardial infarction (AMICS). The purpose was to compare the achievement of treatment targets and outcome in relation to vasoactive strategy in… read more here.
Keywords: scai class; class; mortality; treatment targets ... See more keywords
Metabolomes of mitochondrial diseases and inclusion body myositis patients: treatment targets and biomarkers
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DOI: 10.15252/emmm.201809091
Abstract: Mitochondrial disorders (MDs) are inherited multi‐organ diseases with variable phenotypes. Inclusion body myositis (IBM), a sporadic inflammatory muscle disease, also shows mitochondrial dysfunction. We investigated whether primary and secondary MDs modify metabolism to reveal pathogenic… read more here.
Keywords: treatment targets; treatment; metabolomes mitochondrial; body myositis ... See more keywords
Novel Knowledge about Molecular Mechanisms of Heparin-Induced Thrombocytopenia Type II and Treatment Targets
Sign Up to like & getrecommendations! Published in 2023 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms24098217
Abstract: Heparin-induced thrombocytopenia type II (HIT II), as stated in the literature, occurs in about 3% of all patients and in 0.1–5% of surgical patients. Thrombosis develops in 20–64% of patients with HIT. The mortality rate… read more here.
Keywords: heparin; induced thrombocytopenia; heparin induced; thrombocytopenia type ... See more keywords