Application and investigation of thrombopoiesis-stimulating agents in the treatment of thrombocytopenia
Sign Up to like & getrecommendations! Published in 2023 at "Therapeutic Advances in Hematology"
DOI: 10.1177/20406207231152746
Abstract: Platelets, derived from a certain subpopulation of megakaryocytes, are closely related to hemostasis, coagulation, metastasis, inflammation, and cancer progression. Thrombopoiesis is a dynamic process regulated by various signaling pathways in which thrombopoietin (THPO)–MPL is dominant.… read more here.
Keywords: treatment thrombocytopenia; thrombopoiesis stimulating; thrombopoiesis; stimulating agents ... See more keywords
New Small Molecule Drugs for Thrombocytopenia: Chemical, Pharmacological, and Therapeutic Use Considerations
Sign Up to like & getrecommendations! Published in 2019 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms20123013
Abstract: This review provides details about three small molecules that were recently approved by the FDA for the treatment of thrombocytopenia. The new treatments include lusutrombopag, avatrombopag, and fostamatinib. The first two drugs are orally active… read more here.
Keywords: drugs thrombocytopenia; molecule drugs; small molecule; treatment ... See more keywords