Combination of TREC Measurement and Next-Generation Sequencing in Newborn Screening for Severe Combined Immunodeficiency: A Pilot Program in Japan
Sign Up to like & getrecommendations! Published in 2018 at "Blood"
DOI: 10.1182/blood-2018-99-118261
Abstract: INTRODUCTION Severe combined immunodeficiency disease (SCID) is the most severe form of primary immunodeficiency disorders (PIDs). Impaired cellular and humoral immunity renders the affected infants susceptible to various infections and results in death within the… read more here.
Keywords: immunodeficiency; trec; program; number ... See more keywords
First Year of Israeli Newborn Screening for Severe Combined Immunodeficiency—Clinical Achievements and Insights
Sign Up to like & getrecommendations! Published in 2017 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2017.01448
Abstract: Severe combined immunodeficiency (SCID), the most severe form of T cell immunodeficiency, is detectable through quantification of T cell receptor excision circles (TRECs) in dried blood spots obtained at birth. Herein, we describe the results… read more here.
Keywords: immunodeficiency; first year; trec; scid ... See more keywords
Implementation of TREC/KREC detection protocol for newborn SCID screening in Bulgaria: a pilot study
Sign Up to like & getrecommendations! Published in 2023 at "Central-European Journal of Immunology"
DOI: 10.5114/ceji.2022.124396
Abstract: Neonatal screening for inborn errors of immunity (IEI), based on quantification of T-cell-receptor- excision circles (TRECs) and kappa-deleting recombination-excision circles (KRECs) from dried blood spots (DBS), allows early diagnosis and improved outcomes for the affected… read more here.
Keywords: trec krec; krec detection; implementation trec; trec ... See more keywords