Newborn screening for severe combined immunodeficiency: The results of the first pilot TREC and KREC study in Ukraine with involving of 10,350 neonates
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.999664
Abstract: Severe combined immunodeficiency (SCID) is a group of inborn errors of immunity (IEI) characterized by severe T- and/or B-lymphopenia. At birth, there are usually no clinical signs of the disease, but in the first year… read more here.
Keywords: trec krec; combined immunodeficiency; screening severe; severe combined ... See more keywords
TREC/KREC Levels and T and B Lymphocyte Subpopulations in COVID-19 Patients at Different Stages of the Disease
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DOI: 10.3390/v14030646
Abstract: Background: T and B cell-mediated immunity can be assessed using T cell receptor excision circle (TREC) and Kappa-deleting recombination excision circle (KREC) analysis, respectively, and successful implementation of this method requires evaluation of the correlation… read more here.
Keywords: cell; trec krec; krec levels; cell subsets ... See more keywords
Implementation of TREC/KREC detection protocol for newborn SCID screening in Bulgaria: a pilot study
Sign Up to like & getrecommendations! Published in 2023 at "Central-European Journal of Immunology"
DOI: 10.5114/ceji.2022.124396
Abstract: Neonatal screening for inborn errors of immunity (IEI), based on quantification of T-cell-receptor- excision circles (TRECs) and kappa-deleting recombination-excision circles (KRECs) from dried blood spots (DBS), allows early diagnosis and improved outcomes for the affected… read more here.
Keywords: trec krec; krec detection; implementation trec; trec ... See more keywords