Dominant immune cells in pregnancy and pregnancy complications: T helper cells (TH1/TH2, TH17/Treg cells), NK cells, MDSCs, and the immune checkpoints
Sign Up to like & getrecommendations! Published in 2022 at "Cell Biology International"
DOI: 10.1002/cbin.11955
Abstract: Pregnancy problems including recurrent pregnancy loss, repeated implantation failure and pre‐eclampsia are common problems in the reproductive ages. Different reasons such as genetic, immunological, and environmental agents and also infections could develop these complications. In… read more here.
Keywords: treg cells; immune checkpoints; pregnancy; immune cells ... See more keywords
Treg cell therapy: How cell heterogeneity can make the difference
Sign Up to like & getrecommendations! Published in 2020 at "European Journal of Immunology"
DOI: 10.1002/eji.201948131
Abstract: CD4+CD25highCD127low/−FOXP3+ T regulatory cells are responsible for maintaining immune tolerance and controlling excessive immune responses. Treg cell use in pre‐clinical animal models showed the huge therapeutic potential of these cells in immune‐mediated diseases and laid… read more here.
Keywords: cell therapy; treg cells; cell; treg cell ... See more keywords
Regulatory T‐cell development in the tumor microenvironment
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DOI: 10.1002/eji.202149358
Abstract: Regulatory T (Treg) cells are required for maintaining self‐tolerance and preventing the development of autoimmune diseases. However, Treg cells are abundant in tumors and suppress antitumor immunity, contributing to tumor development and growth. Thus, the… read more here.
Keywords: cell; treg; treg cells; development ... See more keywords
Regulatory T cells as a therapeutic approach for inflammatory bowel disease
Sign Up to like & getrecommendations! Published in 2022 at "European Journal of Immunology"
DOI: 10.1002/eji.202250007
Abstract: Foxp3+ T regulatory (Treg) cells suppress inflammation and are essential for maintaining tissue homeostasis. A growing appreciation of tissue‐specific Treg functions has built interest in leveraging the endogenous suppressive mechanisms of these cells into cellular… read more here.
Keywords: disease; treg cells; inflammatory bowel; bowel disease ... See more keywords
Regulatory T and T helper 17 cells: Their roles in preeclampsia
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DOI: 10.1002/jcp.26604
Abstract: Regulatory T (Treg) cells have been identified as key immune regulators and are important to fetal survival within the maternal uterus. T helper 17 (Th17) cells have also emerged as a new subset of effector… read more here.
Keywords: treg cells; regulatory helper; th17 cells; helper cells ... See more keywords
Neuropilin‐1 is present on Foxp3+ T regulatory cell‐derived small extracellular vesicles and mediates immunity against skin transplantation
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Extracellular Vesicles"
DOI: 10.1002/jev2.12237
Abstract: Abstract Among the mechanisms of suppression that T regulatory (Treg) cells exert to control the immune responses, the secretion of small extracellular vesicles (sEV) has been recently proposed as a novel contact‐independent immunomodulatory mechanism. Previous… read more here.
Keywords: treg; extracellular vesicles; treg cells; transplantation ... See more keywords
Overview of LAG-3-Expressing, IL-10-Producing Regulatory T Cells.
Sign Up to like & getrecommendations! Published in 2017 at "Current topics in microbiology and immunology"
DOI: 10.1007/82_2017_59
Abstract: Regulatory T cells (Treg cells) play crucial roles in the induction of peripheral tolerance to self- and foreign-antigens. IL-10-producing regulatory T cells (IL-10-producing Treg cells) constitute a Treg cell subset characterized by the production of… read more here.
Keywords: treg cells; producing treg; regulatory cells; lag ... See more keywords
Treg Cells and Epigenetic Regulation.
Sign Up to like & getrecommendations! Published in 2021 at "Advances in experimental medicine and biology"
DOI: 10.1007/978-981-15-6407-9_6
Abstract: The discovery of the epigenetic regulation of Treg cells, a cell population with fundamental immunoregulatory properties, has shed considerable insights into an understanding of the role of these cells in health and disease. Research over… read more here.
Keywords: cells epigenetic; treg cells; regulation treg; epigenetic regulation ... See more keywords
Adoptive Induced Antigen-Specific Treg Cells Reverse Inflammation in Collagen-Induced Arthritis Mouse Model
Sign Up to like & getrecommendations! Published in 2017 at "Inflammation"
DOI: 10.1007/s10753-017-0704-4
Abstract: Rheumatoid arthritis (RA) is a systemic autoimmune disease that may cause bone damage and worsening disability. Manipulating antigen-specific Treg cells is a promising approach to treat autoimmune disease since the immune suppressive function of Treg… read more here.
Keywords: treg cells; antigen specific; specific treg; arthritis ... See more keywords
Shikonin Controls the Differentiation of CD4+CD25+ Regulatory T Cells by Inhibiting AKT/mTOR Pathway
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DOI: 10.1007/s10753-019-00982-7
Abstract: CD4+CD25+ regulatory T (Treg) cells maintain the function of immune tolerance and the balance of immune cells. Defects in the number and function of Treg cells can induce the development and progression of inflammatory disease.… read more here.
Keywords: treg cells; cells inhibiting; inhibiting akt; cd4 cd25 ... See more keywords
The Role of Decidual PD-1+ Treg Cells in Adverse Pregnancy Outcomes due to Toxoplasma gondii Infection
Sign Up to like & getrecommendations! Published in 2019 at "Inflammation"
DOI: 10.1007/s10753-019-01075-1
Abstract: Toxoplasma gondii infection during pregnancy can result in adverse pregnancy outcomes. Previously, we have reported that these outcomes are associated with the impaired function of decidual Treg cells; however, the detailed mechanisms involved were unclear.… read more here.
Keywords: treg cells; gondii infection; decidual treg; pregnancy outcomes ... See more keywords