Adaptive NK Cells Resist Regulatory T-cell Suppression Driven by IL37
Sign Up to like & getrecommendations! Published in 2018 at "Cancer Immunology Research"
DOI: 10.1158/2326-6066.cir-17-0498
Abstract: Cross-talk between NK cells and Tregs, mediated by IL37 binding its receptor, altered expression of TIM3 and PD-1 on canonical, but not adaptive, NK cells. Increasing adaptive NK cells or blocking Treg suppression mechanisms could… read more here.
Keywords: suppression; canonical cells; treg suppression; cancer ... See more keywords
Treg suppression of immunity within inflamed allogeneic grafts
Sign Up to like & getrecommendations! Published in 2022 at "JCI Insight"
DOI: 10.1172/jci.insight.160579
Abstract: CD4+Foxp3+ regulatory T cells (Tregs) restrain inflammation and immunity. However, the mechanisms underlying Treg suppressor function in inflamed nonlymphoid tissues remain largely unexplored. Here, we restricted immune responses to nonlymphoid tissues and used intravital microscopy… read more here.
Keywords: treg suppression; within inflamed; immunity; immunity within ... See more keywords