CD11b regulates the Treg/Th17 balance in murine arthritis via IL‐6
Sign Up to like & getrecommendations! Published in 2017 at "European Journal of Immunology"
DOI: 10.1002/eji.201646565
Abstract: Th17 cells are often associated with autoimmunity and been shown to be increased in CD11b−/− mice. Here, we examined the role of CD11b in murine collagen‐induced arthritis (CIA). C57BL/6 and CD11b−/− resistant mice were immunized… read more here.
Keywords: cd11b mice; treg th17; cd11b; mice ... See more keywords
Lactobacillus acidophilus inhibits bone loss and increases bone heterogeneity in osteoporotic mice via modulating Treg-Th17 cell balance
Sign Up to like & getrecommendations! Published in 2018 at "Bone Reports"
DOI: 10.1016/j.bonr.2018.02.001
Abstract: Osteoporosis is one of the most important but often neglected bone disease associated with aging and postmenopausal condition leading to bone loss and fragility. Probiotics have been associated with various immunomodulatory properties and have the… read more here.
Keywords: treg th17; th17 cell; cell balance; th17 ... See more keywords
Astragalus membranaceus improves therapeutic efficacy of asthmatic children by regulating the balance of Treg/Th17 cells.
Sign Up to like & getrecommendations! Published in 2019 at "Chinese journal of natural medicines"
DOI: 10.1016/s1875-5364(19)30029-9
Abstract: Astragalus membranaceus may be a potential therapy for childhood asthma but its driving mechanism remains elusive. The main components of A. membranaceus were identified by HPLC. The children with asthma remission were divided into two… read more here.
Keywords: treg th17; treatment group; th17 cells; control group ... See more keywords
Luteolin restored Treg/Th17 balance to ameliorate allergic rhinitis in a mouse model.
Sign Up to like & getrecommendations! Published in 2023 at "Immunopharmacology and immunotoxicology"
DOI: 10.1080/08923973.2023.2166527
Abstract: OBJECTIVE Luteolin (LO) has been reported to be a potential drug for allergic rhinitis (AR). This paper explored the mechanism of LO in AR. MATERIALS AND METHODS Mice were treated with ovalbumin (OVA) to construct… read more here.
Keywords: treg th17; allergic rhinitis; th17 balance; model ... See more keywords
miR-106b-5p induces immune imbalance of Treg/Th17 in immune thrombocytopenic purpura through NR4A3/Foxp3 pathway
Sign Up to like & getrecommendations! Published in 2020 at "Cell Cycle"
DOI: 10.1080/15384101.2020.1746485
Abstract: ABSTRACT Background Immune imbalance of regulatory T cells (Treg)/T helper 17 cells (Th17) contributes to the development of immune thrombocytopenic purpura (ITP). The dysregulation of miRNAs is important in the development of ITP. However, the… read more here.
Keywords: imbalance; mir 106b; immune imbalance; treg th17 ... See more keywords
Chronic intermittent hypoxia promotes the development of experimental non-alcoholic steatohepatitis by modulating Treg/Th17 differentiation
Sign Up to like & getrecommendations! Published in 2018 at "Acta Biochimica et Biophysica Sinica"
DOI: 10.1093/abbs/gmy131
Abstract: The present study aims to characterize the effect of chronic intermittent hypoxia and HIF1α on the non-alcoholic steatohepatitis (NASH) process in mice, and to explore the role of the Treg/Th17 balance in the formation of… read more here.
Keywords: treg th17; hif1; intermittent hypoxia; chronic intermittent ... See more keywords
Treg/Th17 Ratio Regulation may Play an Important Role in Epigallocatechin-3-Gallate-Mediated Attenuation of Increased Afterload-Induced Cardiac Hypertrophy.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of cardiovascular pharmacology"
DOI: 10.1097/fjc.0000000000001220
Abstract: ABSTRACT The aim of this study was to investigate whether Treg/Th17 ratio regulation plays an important role in epigallocatechin-3-gallate (EGCG) in attenuating increased afterload-induced cardiac hypertrophy. 3-month-old male C57BL/6 mice were divided into sham+vehicle, abdominal… read more here.
Keywords: vehicle; hypertrophy; treg th17; vehicle group ... See more keywords
Dimethyl fumarate modulates the Treg–Th17 cell axis in patients with psoriasis *
Sign Up to like & getrecommendations! Published in 2020 at "British Journal of Dermatology"
DOI: 10.1111/bjd.19229
Abstract: Dimethyl fumarate (DMF) is the active ingredient of Skilarence™ and Tecfidera™, which are used for the treatment of psoriasis and multiple sclerosis, respectively. Various immunomodulatory mechanisms of action have been identified for DMF; however, it… read more here.
Keywords: patients psoriasis; treg th17; fumarate modulates; modulates treg ... See more keywords
SAT0378 The trend of treg and th17 cells changes in p2x7r-regulated acute gouty arthritis model rats
Sign Up to like & getrecommendations! Published in 2018 at "Annals of the Rheumatic Diseases"
DOI: 10.1136/annrheumdis-2018-eular.6136
Abstract: Background ATP may be the second causative signal for the onset of gout, which acts on P2 × 7R to regulate the development of acute gouty arthritis.1Both regulatory T cells and Th17 cells are important… read more here.
Keywords: treg th17; hour; gouty arthritis; acute gouty ... See more keywords
Hedgehog Signaling Regulates Treg to Th17 Conversion Through Metabolic Rewiring in Breast Cancer.
Sign Up to like & getrecommendations! Published in 2023 at "Cancer immunology research"
DOI: 10.1158/2326-6066.cir-22-0426
Abstract: The tumor immune microenvironment dynamically evolves to support tumor growth and progression. Immunosuppressive regulatory T cells (Treg) promote tumor growth and metastatic seeding in patients with breast cancer. Deregulation of plasticity between Treg and Th17… read more here.
Keywords: breast cancer; cancer; treg th17; hedgehog signaling ... See more keywords
Losartan Attenuates Atherosclerosis in Uremic Mice by Regulating Treg/Th17 Balance via Mediating PTEN/PI3K/Akt Pathway
Sign Up to like & getrecommendations! Published in 2022 at "Nephron"
DOI: 10.1159/000521770
Abstract: Introduction: Uremia could accelerate atherosclerosis (AS) formation involving Treg/Th17 imbalance. Losartan regulates the imbalance between regulatory T cells (Treg cells) and T helper 17 cells (Th17 cells). However, their interactions in uremia accelerated AS (UAAS)… read more here.
Keywords: th17 cells; regulating treg; treg th17; uaas mice ... See more keywords