Expression of an interleukin-2 partial agonist enhances regulatory T cell persistence and efficacy in mouse autoimmune models
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DOI: 10.1038/s41467-025-60082-z
Abstract: Regulatory T (Treg)-based cell therapy holds promise for autoimmune and inflammatory diseases, yet challenges remain regarding the functional stability and persistence of transferred Tregs. Here we engineer Tregs to express a partial agonist form of… read more here.
Keywords: tregs il2pa; tregs; persistence; treg ... See more keywords