Hexokinase 2: The preferential target of trehalose‐6‐phosphate over hexokinase 1
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Cellular Biochemistry"
DOI: 10.1002/jcb.30317
Abstract: Cancer‐related metabolic features are in part maintained by hexokinase 2 upregulation, which leads to high levels of glucose‐6‐phosphate (G6P) and is needed to provide energy and biomass to support rapid proliferation. Using a humanized model… read more here.
Keywords: target trehalose; trehalose phosphate; hexokinase preferential; preferential target ... See more keywords
Trehalose‐6‐phosphate synthase influences polysaccharide synthesis and cell wall components in Ganoderma lucidum
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Basic Microbiology"
DOI: 10.1002/jobm.202200279
Abstract: Trehalose‐6‐phosphate synthase (TPS) is a key enzyme that participates in trehalose metabolism, which can synthesize trehalose in a two‐step pathway with trehalose phosphatase, but its role in fungi is rarely studied, especially in large basidiomycetes.… read more here.
Keywords: cell; cell wall; trehalose phosphate; ganoderma lucidum ... See more keywords
Evolution and expression patterns of the trehalose-6-phosphate synthase gene family in drumstick tree (Moringa oleifera Lam.)
Sign Up to like & getrecommendations! Published in 2018 at "Planta"
DOI: 10.1007/s00425-018-2945-3
Abstract: Main conclusionMoringa oleifera TPSs were genome-wide identified for the first time, and a phylogenetic analysis was performed to investigate evolutionary divergence. The qRT-PCR data show that MoTPS genes response to different stress treatments.The trehalose-6-phosphate synthase… read more here.
Keywords: oleifera; expression patterns; group; family ... See more keywords
Involvement of trehalose‐6‐phosphate synthase in innate immunity of Musca domestica
Sign Up to like & getrecommendations! Published in 2019 at "Developmental and Comparative Immunology"
DOI: 10.1016/j.dci.2018.10.010
Abstract: ABSTRACT Trehalose‐6‐phosphate synthase (TPS) is responsible for synthesizing trehalose, which is prevalent in crustaceans and insects as blood‐sugar. In this paper, a TPS gene from Musca domestica(MdTPS)has been cloned and characterized. MdTPS promoter was analyzed,… read more here.
Keywords: mdtps; musca domestica; trehalose phosphate; phosphate synthase ... See more keywords
Characterization and expression pattern of the trehalose-6-phosphate synthase and trehalose-6-phosphate phosphatase gene families in Populus.
Sign Up to like & getrecommendations! Published in 2021 at "International journal of biological macromolecules"
DOI: 10.1016/j.ijbiomac.2021.07.096
Abstract: Trehalose plays an important role in plant metabolism, growth development, and stress tolerance. Trehalose-6-phosphate synthase gene (TPS) and trehalose-6-phosphate phosphatase gene (TPP) are vital for the synthesis of trehalose. Populus is a prominent perennial woody… read more here.
Keywords: phosphate phosphatase; phosphate synthase; expression; trehalose phosphate ... See more keywords
A suicide inhibitor of nematode trehalose-6-phosphate phosphatases
Sign Up to like & getrecommendations! Published in 2019 at "Scientific Reports"
DOI: 10.1038/s41598-019-52593-9
Abstract: Protein-based drug discovery strategies have the distinct advantage of providing insights into the molecular mechanisms of chemical effectors. Currently, there are no known trehalose-6-phosphate phosphatase (TPP) inhibitors that possess reasonable inhibition constants and chemical scaffolds… read more here.
Keywords: suicide inhibitor; inhibitor; nematode; trehalose phosphate ... See more keywords
Trehalose 6-phosphate signalling and impact on crop yield
Sign Up to like & getrecommendations! Published in 2020 at "Biochemical Society Transactions"
DOI: 10.1042/bst20200286
Abstract: The domestication and breeding of crops has been a major achievement for mankind enabling the development of stable societies and civilisation. Crops have become more productive per unit area of cultivated land over the course… read more here.
Keywords: crop; yield; resource allocation; trehalose phosphate ... See more keywords
The Arabidopsis thaliana trehalose-6-phosphate phosphatase gene AtTPPI enhances drought tolerance by regulating stomatal apertures.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of experimental botany"
DOI: 10.1093/jxb/eraa173
Abstract: Transpiration occurs through stomata. The alteration of stomatal apertures in response to drought stress is an important process associated with water use efficiency (WUE). Trehalose-6-phosphate phosphatase (TPP) family genes have been reported to participate in… read more here.
Keywords: stomatal apertures; phosphate phosphatase; drought tolerance; trehalose phosphate ... See more keywords
Rising rates of starch degradation during daytime and trehalose 6-phosphate optimize carbon availability
Sign Up to like & getrecommendations! Published in 2022 at "Plant Physiology"
DOI: 10.1093/plphys/kiac162
Abstract: Abstract Many plants, including Arabidopsis (Arabidopsis thaliana), accumulate starch in the light and remobilize it to support maintenance and growth at night. Starch synthesis and degradation are usually viewed as temporally separate processes. Recently, we… read more here.
Keywords: trehalose phosphate; starch; degradation light; starch degradation ... See more keywords
The Role of Trehalose 6-Phosphate in Crop Yield and Resilience1[OPEN]
Sign Up to like & getrecommendations! Published in 2018 at "Plant Physiology"
DOI: 10.1104/pp.17.01634
Abstract: T6P can be targeted through genetic and chemical methods for crop yield improvements in different environments through the effect of T6P on carbon allocation and biosynthetic pathways. read more here.
Keywords: crop yield; trehalose phosphate; phosphate crop; role trehalose ... See more keywords
Trehalose-6-phosphate phosphatases are involved in the trehalose synthesis and metamorphosis in Bactrocera minax.
Sign Up to like & getrecommendations! Published in 2022 at "Insect science"
DOI: 10.1111/1744-7917.13010
Abstract: Trehalose is the principal sugar circulating in the haemolymph of insects, and the trehalose synthesis is catalyzed by trehalose-6-phosphate synthase (TPS) and trehalose-6-phosphate phosphatase (TPP). Insect TPS is a fused enzyme containing both TPS domain… read more here.
Keywords: bactrocera minax; insects; involved trehalose; trehalose synthesis ... See more keywords