The Chiral Bioconversion and Pharmacokinetic Analysis of Trelagliptin in Beagle Dog Plasma by LC-MS/MS.
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DOI: 10.1093/chromsci/bmz105
Abstract: A simple and enantioselective method was developed and validated for the simultaneous determination of (R)- and (S)-trelagliptin in beagle dog plasma by chiral liquid chromatography tandem mass spectrometry. Trelagliptin enantiomers and (R)-rabeprazole (as internal standard,… read more here.
Keywords: trelagliptin beagle; beagle dog; trelagliptin; dog plasma ... See more keywords