TREM-1 is required for enhanced OpZ-induced superoxide generation following priming.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of leukocyte biology"
DOI: 10.1002/jlb.3a0421-212r
Abstract: Inflammatory agents, microbial products, or stromal factors pre-activate or prime neutrophils to respond to activating stimuli in a rapid and aggressive manner. Primed neutrophils exhibit enhanced chemotaxis, phagocytosis, and respiratory burst when stimulated by secondary… read more here.
Keywords: trem; enhanced opz; trem required; opz induced ... See more keywords
Induced Pluripotent Stem Cells Regulate Triggering Receptor Expressed on Myeloid Cell‐1 Expression and the p38 Mitogen‐Activated Protein Kinase Pathway in Endotoxin‐Induced Acute Lung Injury
Sign Up to like & getrecommendations! Published in 2019 at "STEM CELLS"
DOI: 10.1002/stem.2980
Abstract: Induced pluripotent stem cells (iPSCs) can attenuate the pathological severity and neutrophil migration of lipopolysaccharide (LPS)‐induced acute lung injury (ALI). However, interactions that may occur between iPSCs and the triggering receptor expressed on myeloid cells… read more here.
Keywords: stem cells; p38; expression; trem ... See more keywords
Utility of neutrophil CD64 and serum TREM-1 in distinguishing bacterial infection from disease flare in SLE and ANCA-associated vasculitis
Sign Up to like & getrecommendations! Published in 2018 at "Clinical Rheumatology"
DOI: 10.1007/s10067-018-4334-5
Abstract: Bacterial and opportunistic infections are a major cause of morbidity and mortality in patients with systemic lupus erythematosus (SLE) and antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis owing to treatment with immunosuppressants. Commonly used laboratory tests are… read more here.
Keywords: vasculitis; bacterial infection; infection; disease ... See more keywords
TREM-1 Exacerbates Neuroinflammatory Injury via NLRP3 Inflammasome-Mediated Pyroptosis in Experimental Subarachnoid Hemorrhage.
Sign Up to like & getrecommendations! Published in 2020 at "Translational stroke research"
DOI: 10.1007/s12975-020-00840-x
Abstract: Neuroinflammation contributes to the pathogenesis of early brain injury induced by subarachnoid hemorrhage (SAH). Previous reports have demonstrated that triggering receptor expressed on myeloid cells 1 (TREM-1) regulates inflammatory response caused by ischemic stroke or… read more here.
Keywords: pyroptosis; subarachnoid hemorrhage; nlrp3 inflammasome; injury ... See more keywords
Activation of TREM-1 induces endoplasmic reticulum stress through IRE-1α/XBP-1s pathway in murine macrophages.
Sign Up to like & getrecommendations! Published in 2021 at "Molecular immunology"
DOI: 10.1016/j.molimm.2021.04.023
Abstract: Increasing evidence suggests that endoplasmic reticulum (ER) stress activates several pro-inflammatory signaling pathways in many diseases, including acute lung injury (ALI). We have reported that blocking triggering receptor expressed on myeloid cells 1 (TREM-1) protects… read more here.
Keywords: ire xbp; stress; pro inflammatory; trem ... See more keywords
Potentiation of NETs release is novel characteristic of TREM-1 activation and the pharmacological inhibition of TREM-1 could prevent from the deleterious consequences of NETs release in sepsis
Sign Up to like & getrecommendations! Published in 2021 at "Cellular and Molecular Immunology"
DOI: 10.1038/s41423-020-00591-7
Abstract: During sepsis, neutrophil activation induces endothelial cell (EC) dysfunction partly through neutrophil extracellular trap (NET) release. The triggering receptor expressed on myeloid cell-1 (TREM-1) is an orphan immune receptor that amplifies the inflammatory response mediated… read more here.
Keywords: potentiation nets; activation; nets release; inhibition trem ... See more keywords
Triggering receptor expressed on myeloid cells in the pathogenesis of periodontitis: potential novel treatment strategies
Sign Up to like & getrecommendations! Published in 2017 at "Expert Review of Clinical Immunology"
DOI: 10.1080/1744666x.2017.1392855
Abstract: ABSTRACT Introduction: Periodontal diseases are polymicrobial inflammatory disorders of the tissue, ligament, and bone structures supporting teeth. Periodontitis (inflammation with corresponding loss of attachment) affects 40–50% of adults. Recently, members of the Triggering Receptor on… read more here.
Keywords: expressed myeloid; inflammation; receptor expressed; triggering receptor ... See more keywords
Dengue Virus Increases the Expression of TREM-1 and CD10 on Human Neutrophils.
Sign Up to like & getrecommendations! Published in 2023 at "Viral immunology"
DOI: 10.1089/vim.2022.0124
Abstract: Every year, dengue is responsible for 400 million infections worldwide. Inflammation is related to the development of severe forms of dengue. Neutrophils are a heterogeneous cell population with a key role in the immune response.… read more here.
Keywords: trem; human neutrophils; infection; dengue ... See more keywords
Targeted endothelial gene deletion of triggering receptor expressed on myeloid cells-1 protects mice during septic shock
Sign Up to like & getrecommendations! Published in 2018 at "Cardiovascular Research"
DOI: 10.1093/cvr/cvy018
Abstract: Aims TREM-1 (Triggering Receptor Expressed on Myeloid cells-1) is an immunoreceptor expressed on neutrophils and monocytes/macrophages whose role is to amplify the inflammatory response driven by Toll-Like Receptors engagement. The pharmacological inhibition of TREM-1 confers… read more here.
Keywords: septic shock; receptor expressed; triggering receptor; deletion ... See more keywords
Importance of conserving large and old trees to continuity of tree‐related microhabitats
Sign Up to like & getrecommendations! Published in 2023 at "Conservation Biology"
DOI: 10.1111/cobi.14066
Abstract: Protecting structural features, such as tree‐related microhabitats (TreMs), is a cost‐effective tool crucial for biodiversity conservation applicable to large forested landscapes. Although the development of TreMs is influenced by tree diameter, species, and vitality, the… read more here.
Keywords: trem; diameter; tree related; related microhabitats ... See more keywords
Response for “Letter to editor: Evaluation of the relationship between TREM‐1/TREM 2 ratio and clinical course in COVID‐19 pneumonia”
Sign Up to like & getrecommendations! Published in 2021 at "International Journal of Clinical Practice"
DOI: 10.1111/ijcp.14928
Abstract: Thank you for your interest in our article. First of all, we would like to point out that TREM1 and TREM2, which we have measured, are nonsoluble forms. Since we know the effects of treatment… read more here.
Keywords: trem; response letter; evaluation relationship; relationship trem ... See more keywords