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   Articles with "trem1" as a keyword



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Low TREM1 expression in whole blood predicts anti-TNF response in inflammatory bowel disease

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recommendations! Published in 2019 at "EBioMedicine"

DOI: 10.1016/j.ebiom.2019.01.027

Abstract: Background With the changed therapeutic armamentarium for Crohn's disease (CD) and ulcerative colitis (UC), biomarkers predicting treatment response are urgently needed. We studied whole blood and mucosal expression of genes previously reported to predict outcome… read more here.

Keywords: tnf; trem1; anti tnf; expression ... See more keywords
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Upstream stimulatory factor 2 (USF2) induced upregulation of triggering receptor expressed on myeloid cells 1 (TREM1) promotes endometritis by regulating toll-like receptor (TLR) 2/4-nuclear factor-kappaB (NF-κB) signaling pathway

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recommendations! Published in 2022 at "Bioengineered"

DOI: 10.1080/21655979.2022.2030619

Abstract: ABSTRACT Triggering receptor expressed on myeloid cells 1 (TREM1) participates in the development of endometritis. This study aims at identifying the effects and interaction of TREM1 and upstream stimulatory factor 2 (USF2) in endometritis by… read more here.

Keywords: signaling pathway; receptor expressed; triggering receptor; factor ... See more keywords
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Letter to editor: Evaluation of the relationship between TREM‐1/TREM‐2 ratio and clinical course in COVID‐19 pneumonia

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recommendations! Published in 2021 at "International Journal of Clinical Practice"

DOI: 10.1111/ijcp.14929

Abstract: Dear editor, we read with great interest the wellwritten article by Dr Kerget et al with the main objective of investigating the role of the TREM1/TREM2 ratio on patients with COVID19 pneumonia.1 The article pointed… read more here.

Keywords: trem1; trem; trem2 ratio; clinical course ... See more keywords
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TREM1 fosters an immunosuppressive tumor microenvironment in papillary thyroid cancer.

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recommendations! Published in 2021 at "Endocrine-related cancer"

DOI: 10.1530/erc-21-0297

Abstract: The immunosuppressive microenvironment is associated with poor prognosis in papillary thyroid cancer (PTC); however, the molecular mechanisms involved are unknown. Among triggering receptor expressed on myeloid cell (TREM) family, we found that TREM1 expression in… read more here.

Keywords: thyroid cancer; microenvironment; trem1; papillary thyroid ... See more keywords
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Overexpression of TREM1 is Associated with the Immune-Suppressive Microenvironment and Unfavorable Prognosis in Pan-Cancer

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recommendations! Published in 2023 at "Journal of Inflammation Research"

DOI: 10.2147/jir.s398284

Abstract: Background Triggering receptors expressed by myeloid cells-1 (TREM1) is a receptor belonging to the immunoglobulin superfamily and plays an important role in pro-inflammation in acute and chronic inflammatory disorders. However, the understanding of the immunomodulatory… read more here.

Keywords: prognosis; overexpression trem1; pan cancer; analysis ... See more keywords
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SLAMF7 and TREM1 Mediate Immunogenic Cell Death in Colorectal Cancer Cells: Focus on Microsatellite Stability

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recommendations! Published in 2021 at "AntiCancer Research"

DOI: 10.21873/anticanres.15355

Abstract: Background/Aim: The aim of this study was to identify the association between SLAMF7 and TREM1 and anti-PD-1 drugs, and to determine whether they are molecular targets or predictors of responses to immunotherapy through induction of… read more here.

Keywords: immunogenic cell; trem1; slamf7; cell death ... See more keywords
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Persistent DNA damage and oncogenic stress-induced Trem1 promotes leukemia in mice

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recommendations! Published in 2022 at "Haematologica"

DOI: 10.3324/haematol.2021.280404

Abstract: The immune receptor TREM1 (Triggering receptor expressed on myeloid cells 1) is a master regulator of inflammatory response. Compelling evidence suggests important pathological roles for TREM1 in various types of solid tumors. However, the role… read more here.

Keywords: hsc lsc; dna damage; pre leukemic; trem1 ... See more keywords