Articles with "treo" as a keyword



Differential Toxicity Profile of Busulfan and Treosulfan on Endothelial Cells - Relevance to Hematopoietic Stem Cell Transplantation

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Published in 2019 at "Biology of Blood and Marrow Transplantation"

DOI: 10.1016/j.bbmt.2018.12.778

Abstract: The success of Hematopoietic stem cell transplantation (HSCT), an established curative treatment option for hematological malignancies and non-malignant diseases, is often limited by regimen related toxicity (RRT) caused by conditioning regimen drugs. Despite their intended… read more here.

Keywords: bone marrow; toxicity; treo; day ... See more keywords
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Disposition of treosulfan and its active monoepoxide in a bone marrow, liver, lungs, brain, and muscle: Studies in a rat model with clinical relevance

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Published in 2017 at "European Journal of Pharmaceutical Sciences"

DOI: 10.1016/j.ejps.2017.09.011

Abstract: &NA; For the recent years, the application of treosulfan (TREO)‐based conditioning prior to hematopoietic stem cell transplantation (HSCT) has been increasing as an alternative to busulfan‐based therapy, especially for patients presenting high risk of developing… read more here.

Keywords: brain; treo; liver lungs; bone marrow ... See more keywords
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Relationship between exposure to treosulfan and its monoepoxytransformer – An insight from population pharmacokinetic study in pediatric patients before hematopoietic stem cell transplantation

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Published in 2018 at "European Journal of Pharmaceutical Sciences"

DOI: 10.1016/j.ejps.2018.04.036

Abstract: &NA; Treosulfan (TREO), a structural analog of busulfan, is currently studied as a myeloablative agent in conditioning regimens before hematopoietic stem cell transplantation in pediatric patients. High exposure to TREO (>1650 mg*h/mL) might be related… read more here.

Keywords: population pharmacokinetic; treo; exposure; exposure treo ... See more keywords
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The Bolton Treo endograft for treatment of abdominal aortic aneurysms: just another trimodular platform?

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Published in 2018 at "Expert Review of Medical Devices"

DOI: 10.1080/17434440.2018.1419864

Abstract: ABSTRACT Introduction: The Treo abdominal aortic stent graft system (Bolton Medical, Barcelona, Spain) is a trimodular endovascular endoprosthesis recently introduced for the endovascular repair of abdominal aortic aneurysms (AAA). It presents some unique structural characteristics… read more here.

Keywords: bolton treo; treo; aortic aneurysms; platform ... See more keywords
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Propiedades biomecánicas de la membrana limitante interna tras recibir tratamiento intravítreo con ocriplasmina

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Published in 2017 at "Ophthalmologica"

DOI: 10.1159/000477510

Abstract: Objetivo: Evaluar la rigidez de la membrana limitante interna (MLI) humana y evaluar los posibles cambios de las propiedades mecánicas tras administrar una inyección intravítrea de ocriplasmina para tratar la tracción vitreomacular. Métodos: Este estudio… read more here.

Keywords: con ocriplasmina; con; treo; mli ... See more keywords