Possible effects of Treponema pallidum infection on human vascular endothelial cells
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Clinical Laboratory Analysis"
DOI: 10.1002/jcla.24318
Abstract: Pathogens can affect host cells in various ways, and the same effect can be found in the Treponema pallidum acting on the endothelium of host vessels, and the mechanism is often complex and multiple. Based… read more here.
Keywords: endothelial cells; treponema pallidum; vascular endothelial; pallidum infection ... See more keywords
Relationship between DiaSorin Liaison Treponema pallidum antibody indices and confirmatory assay results in the reverse syphilis testing algorithm.
Sign Up to like & getrecommendations! Published in 2020 at "Diagnostic microbiology and infectious disease"
DOI: 10.1016/j.diagmicrobio.2020.115303
Abstract: Published studies show that >99% of sera reactive in the reverse syphilis testing algorithm (RSTA) screening assay with an index above an assay-specific threshold confirm as reactive, with either a rapid plasma reagin-reactive (RPRR) or… read more here.
Keywords: treponema pallidum; testing algorithm; indices confirmatory; syphilis testing ... See more keywords
Evaluation of ELISA and CLIA for Treponema pallidum specific antibody detection in China: A multicenter study.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of microbiological methods"
DOI: 10.1016/j.mimet.2019.105742
Abstract: BACKGROUND Considering the rapid increase of syphilis infections in several countries including China, searching for a screening test with sufficient sensitivity and specificity is extremely urgent. The current study mainly researched the performance for Treponema… read more here.
Keywords: treponema pallidum; detection; study; elisa ... See more keywords
A defined syphilis vaccine candidate inhibits dissemination of Treponema pallidum subspecies pallidum
Sign Up to like & getrecommendations! Published in 2017 at "Nature Communications"
DOI: 10.1038/ncomms14273
Abstract: Syphilis is a prominent disease in low- and middle-income countries, and a re-emerging public health threat in high-income countries. Syphilis elimination will require development of an effective vaccine that has thus far remained elusive. Here… read more here.
Keywords: treponema pallidum; vaccine candidate; syphilis vaccine; vaccine ... See more keywords
Treponema pallidum outer membrane proteins: current status and prospects.
Sign Up to like & getrecommendations! Published in 2022 at "Pathogens and disease"
DOI: 10.1093/femspd/ftac023
Abstract: The outer membrane proteins (OMPs) of Treponema pallidum subsp. Pallidum (T. pallidum), the etiological agent of the sexually transmitted disease syphilis, has long been a hot research topic. Despite many hurdles to studying the pathogen, especially the inability to manipulate T.… read more here.
Keywords: membrane proteins; pallidum; outer membrane; treponema pallidum ... See more keywords
Evolutionary Processes in the Emergence and Recent Spread of the Syphilis Agent, Treponema pallidum
Sign Up to like & getrecommendations! Published in 2021 at "Molecular Biology and Evolution"
DOI: 10.1093/molbev/msab318
Abstract: Abstract The incidence of syphilis has risen worldwide in the last decade in spite of being an easily treated infection. The causative agent of this sexually transmitted disease is the bacterium Treponema pallidum subspecies pallidum… read more here.
Keywords: evolutionary processes; treponema pallidum; pallidum; agent ... See more keywords
Treponema pallidum Strains Among Women and Men Who Have Sex With Women in Amsterdam, the Netherlands and Antwerp, Belgium Between 2014 and 2020
Sign Up to like & getrecommendations! Published in 2023 at "Sexually Transmitted Diseases"
DOI: 10.1097/olq.0000000000001779
Abstract: A different Treponema pallidum strain distribution was found among samples derived from men who have sex with women and women from this study as compared with the same population worldwide. read more here.
Keywords: among women; pallidum strains; sex women; treponema pallidum ... See more keywords
Whole genome sequence of a Treponema pallidum strain from a formalin-fixed paraffin-embedded fine needle aspirate of a cervical lymph node.
Sign Up to like & getrecommendations! Published in 2023 at "Sexually transmitted diseases"
DOI: 10.1097/olq.0000000000001827
Abstract: ABSTRACT A patient with unilateral cervical lymphadenopathy suspicious for malignancy underwent a fine needle aspiration. Histology demonstrated mixed inflammatory infiltrates with abundant spirochetes. Sufficient spirochete DNA was extracted from paraffin-embedded tissue sections to obtain the… read more here.
Keywords: fine needle; treponema pallidum; genome sequence; paraffin embedded ... See more keywords
Diagnostic value of Treponema pallidum PCR test in real practice
Sign Up to like & getrecommendations! Published in 2023 at "Australasian Journal of Dermatology"
DOI: 10.1111/ajd.13964
Abstract: Syphilis is a sexually transmitted infection (STI) caused by the pathogen Treponema pallidum. Its incidence is increasing in our country, especially among men who have sex with men (MSM). Serological tests are still the most… read more here.
Keywords: value treponema; treponema; pallidum pcr; treponema pallidum ... See more keywords
Treponema pallidum membrane protein Tp47 promotes angiogenesis through ROS‐induced autophagy
Sign Up to like & getrecommendations! Published in 2022 at "Journal of the European Academy of Dermatology and Venereology"
DOI: 10.1111/jdv.18728
Abstract: Pathological angiogenesis is an important manifestation of syphilis, but the underlying mechanism of Treponema pallidum subspecies pallidum (T. pallidum)‐induced angiogenesis is poorly understood. read more here.
Keywords: pallidum; pallidum membrane; membrane protein; treponema pallidum ... See more keywords
Treponema pallidum Nucleic Acid Amplification Testing To Augment Syphilis Screening among Men Who Have Sex with Men
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Clinical Microbiology"
DOI: 10.1128/jcm.00572-19
Abstract: Syphilis rates in much of the world are now at their highest levels in almost three decades, and new approaches to controlling syphilis, including diagnostic tests with shorter window periods, are urgently needed. ABSTRACT Syphilis… read more here.
Keywords: treponema pallidum; sex men; syphilis; men sex ... See more keywords