Identification of a novel tRNA‐derived RNA fragment exhibiting high prognostic potential in chronic lymphocytic leukemia
Sign Up to like & getrecommendations! Published in 2019 at "Hematological Oncology"
DOI: 10.1002/hon.2616
Abstract: tRNA-derived fragments (tRFs) are 16-28 nucleotide fragments, which occur by specific cleavage of tRNA molecules. i-tRF-GlyGCC is an internal tRF, originating from the tRNAs bearing the Glycine anticodon "GCC". Other tRFs generated from tRNAGlyGCC have… read more here.
Keywords: trna derived; analysis; trf; leukemia ... See more keywords
Dimethyl fumarate vs Teriflunomide: an Italian time-to-event data analysis
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Neurology"
DOI: 10.1007/s00415-020-09959-1
Abstract: The introduction of oral disease-modifying therapies (DMTs) for relapsing–remitting multiple sclerosis (RRMS) changed algorithms of RRMS treatment. To compare the effectiveness of treatment with dimethyl fumarate (DMF) and teriflunomide (TRF) in a large multicentre Italian… read more here.
Keywords: trf; treatment; time; dimethyl fumarate ... See more keywords
Time-restricted feeding is associated with changes in human gut microbiota related to nutrient intake.
Sign Up to like & getrecommendations! Published in 2020 at "Nutrition"
DOI: 10.1016/j.nut.2020.110797
Abstract: OBJECTIVES Time-restricted feeding (TRF) is a dietary therapeutic remedy for the prevention and treatment of metabolic diseases. Gut microbiota may influence the host metabolism and nutritional status of individuals. Given the significance of TRF and… read more here.
Keywords: trf; trf group; gut microbiota;
Research progress on the tsRNA classification, function, and application in gynecological malignant tumors
Sign Up to like & getrecommendations! Published in 2021 at "Cell Death Discovery"
DOI: 10.1038/s41420-021-00789-2
Abstract: A large number of small non-coding RNAs derived from tRNAs, called tRNA-derived small RNA (tsRNAs), have been identified by high-throughput RNA sequencing of cell lines. Further research has revealed that they are not produced via… read more here.
Keywords: trf; research progress; classification; research ... See more keywords
Impact of combining pulsed and thermal radiofrequency on long-term therapy of idiopathic trigeminal neuralgia: A prospective study
Sign Up to like & getrecommendations! Published in 2020 at "Egyptian Journal of Anaesthesia"
DOI: 10.1080/11101849.2020.1762460
Abstract: ABSTRACT Background Trigeminal neuralgia (TN) is a painful condition characterized by sudden onset, severe unilateral, brief, stabbing recurrent episodes electric shock like pain in the distribution of one or more branches of the trigeminal nerve.… read more here.
Keywords: long term; trf; radiofrequency; trigeminal neuralgia ... See more keywords
Satiety Associated with Calorie Restriction and Time-restricted Feeding: Peripheral Hormones.
Sign Up to like & getrecommendations! Published in 2022 at "Advances in nutrition"
DOI: 10.1093/advances/nmac014
Abstract: Calorie restriction (CR) is a common approach to inducing negative energy balance. Recently, time-restricted feeding (TRF), which involves consuming food within specific time windows during a 24h day, has become popular owing to its relative ease… read more here.
Keywords: time; trf; satiety; restriction ... See more keywords
[LB.02.29] FEEDING SCHEDULE REDUCES BLOOD PRESSURE BUT DOES NOT PROTECT AGAINST DIET-INDUCED OBESITY IN RATS
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Hypertension"
DOI: 10.1097/01.hjh.0000523754.95393.4a
Abstract: Objective: Evidence in mice indicates that limiting food access to the active phase, termed time-restricted feeding (TRF), can prevent diet-induced obesity without the necessity of reducing food intake (FI). We compared TRF with pharmacological treatment… read more here.
Keywords: diet induced; mtii; blood pressure; trf ... See more keywords
The tRNA-derived fragment 5'tRF-Gly promotes the development of hepatocellular carcinoma via direct targeting of CEACAM1.
Sign Up to like & getrecommendations! Published in 2022 at "Cancer science"
DOI: 10.1111/cas.15505
Abstract: tRNA-derived fragments are a group of small non-coding single-stranded RNA that play essential roles in multiple diseases. However, their biological functions in carcinogenesis are not well understood. In this study, 5'tRF-Gly was found to have… read more here.
Keywords: hepatocellular carcinoma; trf; ceacam1; trna derived ... See more keywords
Peak functional ability and age at loss of ambulation in Duchenne muscular dystrophy.
Sign Up to like & getrecommendations! Published in 2022 at "Developmental medicine and child neurology"
DOI: 10.1111/dmcn.15176
Abstract: AIM To correlate the North Star Ambulatory Assessment (NSAA) and timed rise from floor (TRF) recorded at age of expected peak with age at loss of ambulation (LOA) in Duchenne muscular dystrophy (DMD). METHOD Male… read more here.
Keywords: loss ambulation; trf; duchenne muscular; years months ... See more keywords
tRNA‐derived fragment tRF‐1020 ameliorates diabetes‐induced retinal microvascular complications
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Cellular and Molecular Medicine"
DOI: 10.1111/jcmm.17555
Abstract: Transfer RNA (tRNA)‐derived fragments are the non‐coding single‐stranded RNAs involved in several physiological and pathological processes. Herein, we investigated the role of tRF‐1020, a tRNA fragment, in diabetes‐induced retinal microvascular complications. The results showed that… read more here.
Keywords: trf; retinal microvascular; induced retinal; trf 1020 ... See more keywords
tRNA-Derived Fragment tRF-5009A Regulates Autophagy and Degeneration of Cartilage in Osteoarthritis via Targeting mTOR
Sign Up to like & getrecommendations! Published in 2022 at "Oxidative Medicine and Cellular Longevity"
DOI: 10.1155/2022/5781660
Abstract: tRNA-derived fragments (tRFs) have been reported to have critical regulatory roles in osteoarthritis (OA). Recent studies have suggested that autophagy promotes the homeostasis of the extracellular matrix of chondrocytes in OA. However, the role of… read more here.
Keywords: trf; degeneration; cartilage; expression ... See more keywords