Identification of transfer RNA-derived fragments and their potential roles in aortic dissection.
Sign Up to like & getrecommendations! Published in 2021 at "Genomics"
DOI: 10.1016/j.ygeno.2021.06.039
Abstract: Emerging evidence suggests that majority of the transfer RNA (tRNA)-derived small RNA, including tRNA-derived fragments (tRFs) and tRNA halves (tiRNAs), play a significant role in the molecular mechanisms underlying some human diseases. However, expression of… read more here.
Keywords: roles aortic; trfs tirnas; aortic dissection; transfer rna ... See more keywords
Role of tRNA derived fragments in renal ischemia–reperfusion injury
Sign Up to like & getrecommendations! Published in 2022 at "Renal Failure"
DOI: 10.1080/0886022x.2022.2072336
Abstract: Abstract Background Ischemia–reperfusion injury (IRI) is one of the major causes of acute kidney injury (AKI). tRNA derived fragments (tRFs/tiRNAs) are groups of small noncoding RNAs derived from tRNAs. To date, the role of tRFs/tiRNAs… read more here.
Keywords: reperfusion injury; injury; ischemia reperfusion; trfs tirnas ... See more keywords
Differential Expression Profiles and Function Prediction of Transfer RNA-Derived Fragments in High-Grade Serous Ovarian Cancer
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DOI: 10.1155/2021/5594081
Abstract: Background The present study is aimed at providing systematic insight into the composition and expression of transfer RNA (tRNA) derivative transcription in high-grade serous ovarian cancer (HGSOC). Methods tRNA derivative expression profiles in three pairs… read more here.
Keywords: grade serous; high grade; trfs tirnas; transfer rna ... See more keywords
Differential Expression Profiles and Function Predictions for tRFs & tiRNAs in Skin Injury Induced by Ultraviolet Irradiation
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Cell and Developmental Biology"
DOI: 10.3389/fcell.2021.707572
Abstract: Ultraviolet (UV) radiation is a major environmental factor contributing skin damage. As UV exposure is inevitable, it is necessary to pay attention to the underlying molecular mechanisms of UV-induced skin damage to develop effective therapies.… read more here.
Keywords: trfs tirnas; trf; induced skin; expression ... See more keywords