A novel synthetic trivalent single chain variable fragment (tri-scFv) construction platform based on the SpyTag/SpyCatcher protein ligase system
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DOI: 10.1186/s12896-018-0466-6
Abstract: BackgroundAdvances in antibody engineering provide strategies to construct recombinant antibody-like molecules with modified pharmacokinetic properties. Multermerization is one strategy that has been used to produce antibody-like molecules with two or more antigen binding sites. Multimerization… read more here.
Keywords: spytag; scfv; anti her3; tri ... See more keywords