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   Articles with "trial" as a keyword



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Effect of Ischemic Postconditioning During Primary Percutaneous Coronary Intervention for Patients With ST-Segment Elevation Myocardial Infarction: A Randomized Clinical Trial

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recommendations! Published in 2017 at "JAMA Cardiology"

DOI: 10.1001/jamacardio.2017.0022

Abstract: Importance Ischemic postconditioning of the heart during primary percutaneous coronary intervention (PCI) induced by repetitive interruptions of blood flow to the ischemic myocardial region immediately after reopening of the infarct-related artery may limit myocardial damage.… read more here.

Keywords: trial; primary percutaneous; myocardial infarction; ischemic postconditioning ... See more keywords
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Effect of Resveratrol on Walking Performance in Older People With Peripheral Artery Disease: The RESTORE Randomized Clinical Trial

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recommendations! Published in 2017 at "JAMA Cardiology"

DOI: 10.1001/jamacardio.2017.0538

Abstract: Importance Research shows that resveratrol, a sirtuin activator in red wine, improves exercise endurance and skeletal-muscle oxidative metabolism in animals and may enhance vascular function in humans. Resveratrol supplement sales exceed $30 million annually in… read more here.

Keywords: resveratrol; trial; resveratrol group; group ... See more keywords
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Longitudinal Hemodynamics of Transcatheter and Surgical Aortic Valves in the PARTNER Trial

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recommendations! Published in 2017 at "JAMA Cardiology"

DOI: 10.1001/jamacardio.2017.3306

Abstract: Importance Use of transcatheter aortic valve replacement (TAVR) for severe aortic stenosis is growing rapidly. However, to our knowledge, the durability of these prostheses is incompletely defined. Objective To determine the midterm hemodynamic performance of… read more here.

Keywords: trial; partner; transcatheter heart; aortic valve ... See more keywords
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Cardiovascular Outcomes According to Urinary Albumin and Kidney Disease in Patients With Type 2 Diabetes at High Cardiovascular Risk: Observations From the SAVOR-TIMI 53 Trial

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recommendations! Published in 2018 at "JAMA Cardiology"

DOI: 10.1001/jamacardio.2017.4228

Abstract: Importance An elevated level of urinary albumin to creatinine ratio (UACR) is a marker of renal dysfunction and predictor of kidney failure/death in patients with type 2 diabetes. The prognostic use of UACR in established… read more here.

Keywords: patients type; risk; trial; disease ... See more keywords
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Timing of Loading Dose of Atorvastatin in Patients Undergoing Percutaneous Coronary Intervention for Acute Coronary Syndromes: Insights From the SECURE-PCI Randomized Clinical Trial

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recommendations! Published in 2018 at "JAMA Cardiology"

DOI: 10.1001/jamacardio.2018.3408

Abstract: Importance Loading doses of atorvastatin did not show reduction on clinical outcomes in the overall population of patients with acute coronary syndrome (ACS) enrolled in the Statins Evaluation in Coronary Procedures and Revascularization (SECURE-PCI) trial,… read more here.

Keywords: trial; doses atorvastatin; mace; loading doses ... See more keywords
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Sex-Based Outcomes in Patients With a High Bleeding Risk After Percutaneous Coronary Intervention and 1-Month Dual Antiplatelet Therapy: A Secondary Analysis of the LEADERS FREE Randomized Clinical Trial.

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recommendations! Published in 2020 at "JAMA cardiology"

DOI: 10.1001/jamacardio.2020.0285

Abstract: Importance Female sex has been identified as a risk factor for bleeding after percutaneous coronary intervention (PCI) and may have contributed to the underuse of drug-eluting stents in women. This risk may be further enhanced… read more here.

Keywords: risk; high bleeding; trial; sex ... See more keywords
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Assessment of Limitations to Optimization of Guideline-Directed Medical Therapy in Heart Failure From the GUIDE-IT Trial: A Secondary Analysis of a Randomized Clinical Trial.

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recommendations! Published in 2020 at "JAMA cardiology"

DOI: 10.1001/jamacardio.2020.0640

Abstract: Importance Despite evidence that guideline-directed medical therapy (GDMT) improves outcomes in patients with heart failure (HF) and reduced ejection fraction, many patients are undertreated. The Guiding Evidence-Based Therapy Using Biomarker Intensified Treatment (GUIDE-IT) trial tested… read more here.

Keywords: trial; guideline directed; analysis; medical therapy ... See more keywords
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Effect of a Self-care Intervention on 90-Day Outcomes in Patients With Acute Heart Failure Discharged From the Emergency Department: A Randomized Clinical Trial.

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recommendations! Published in 2020 at "JAMA cardiology"

DOI: 10.1001/jamacardio.2020.5763

Abstract: Importance Up to 20% of patients who present to the emergency department (ED) with acute heart failure (AHF) are discharged without hospitalization. Compared with rates in hospitalized patients, readmission and mortality are worse for ED… read more here.

Keywords: intervention; care intervention; trial; emergency department ... See more keywords
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Association Between Achieved ω-3 Fatty Acid Levels and Major Adverse Cardiovascular Outcomes in Patients With High Cardiovascular Risk: A Secondary Analysis of the STRENGTH Trial.

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recommendations! Published in 2021 at "JAMA cardiology"

DOI: 10.1001/jamacardio.2021.1157

Abstract: Importance In patients treated with ω-3 fatty acids, it remains uncertain whether achieved levels of eicosapentaenoic acid (EPA) or docosahexaenoic acid (DHA) are associated with cardiovascular outcomes. Objective To determine the association between plasma levels… read more here.

Keywords: acid; trial; cardiovascular outcomes; corn oil ... See more keywords
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TET2-Driven Clonal Hematopoiesis and Response to Canakinumab: An Exploratory Analysis of the CANTOS Randomized Clinical Trial.

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recommendations! Published in 2022 at "JAMA cardiology"

DOI: 10.1001/jamacardio.2022.0386

Abstract: Importance Clonal hematopoiesis of indeterminate potential (CHIP) is associated with increased risk of atherosclerotic cardiovascular disease, and mouse experiments suggest that CHIP related to Tet2 loss of function in myeloid cells accelerates atherosclerosis via augmented… read more here.

Keywords: trial; randomized clinical; clinical trial; chip ... See more keywords
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Long-term Effects of P2Y12 Inhibitor Monotherapy After Percutaneous Coronary Intervention: 3-Year Follow-up of the SMART-CHOICE Randomized Clinical Trial.

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recommendations! Published in 2022 at "JAMA cardiology"

DOI: 10.1001/jamacardio.2022.3203

Abstract: Importance Although P2Y12 inhibitor monotherapy after a minimum period of dual antiplatelet therapy (DAPT) is a well-known way to reduce the risk of bleeding after percutaneous coronary intervention (PCI), data comparing long-term clinical outcomes between… read more here.

Keywords: p2y12 inhibitor; long term; inhibitor monotherapy; trial ... See more keywords