The FAITH and HEALTH Trials: Are We Studying Different Hip Fracture Patient Populations?
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Orthopaedic Trauma"
DOI: 10.1097/bot.0000000000001930
Abstract: BACKGROUND Over the past decade, 2 randomized controlled trials were performed to evaluate 2 surgical strategies (internal fixation and arthroplasty) for the treatment of low-energy femoral neck fractures in patients aged ≥50 years. We evaluated… read more here.
Keywords: health; femoral neck; patient populations; faith health ... See more keywords
Optimizing the value of lenalidomide maintenance by genetic profiling - an analysis of 556 Myeloma XI trial patients.
Sign Up to like & getrecommendations! Published in 2022 at "Blood"
DOI: 10.1182/blood.2022018339
Abstract: Prediction of individual patient benefit from lenalidomide (Len) maintenance post autologous transplant (ASCT) remains challenging. We investigated here extended molecular profiling for outcome prediction in NCRI Myeloma XI (MyXI) trial patients. MyXI patients randomized to… read more here.
Keywords: len maintenance; maintenance; risk; trial patients ... See more keywords
Phase II trial of SM-88 in patients with metastatic pancreatic cancer: Preliminary results of the first stage.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2019.37.4_suppl.200
Abstract: 200 Background: SM-88 (tyrosine derivative [Td], mTOR inhibitor, CYP3a4 inducer and oxidative stress catalyst) is a relatively non-toxic, targeted therapy that utilizes the Warburg Effect in combination with oxidative stress to cause tumor cell death.… read more here.
Keywords: phase trial; cancer; first stage; trial ... See more keywords
Differences Between Randomized Clinical Trial Patients and Real-World Initiators of the Glucagon-Like Peptide 1 Receptor Agonist Liraglutide
Sign Up to like & getrecommendations! Published in 2018 at "Diabetes Care"
DOI: 10.2337/dc18-0999
Abstract: Randomized controlled trials (RCTs) are considered the gold standard for determining efficacy and safety of new drugs. Successful randomization addresses known and unknown confounding when assessing a drug’s effect among trial patients selected on strict… read more here.
Keywords: trial; glucagon like; receptor agonist; trial patients ... See more keywords