Participation of Older Adults in Clinical Trials for New Drug Applications and Biologics License Applications From 2010 Through 2019
Sign Up to like & getrecommendations! Published in 2022 at "JAMA Network Open"
DOI: 10.1001/jamanetworkopen.2022.36149
Abstract: Key Points Question Are older adults adequately represented in clinical trials for new drug evaluation? Findings In this cross-sectional study, adults in the oldest age groups above age 75 years or in some therapeutic areas… read more here.
Keywords: older adults; clinical trials; new drug; trials new ... See more keywords
Open data, trials and new ethics of using others' work
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DOI: 10.1136/medethics-2019-105898
Abstract: Data and ideas are the capital of research productivity. Is it ethical to preempt the publication of another researcher’s unpublished data or preliminary analysis, perhaps without citation? The long-established answer is ‘certainly not’—but recent ‘open… read more here.
Keywords: trials new; new ethics; open data; ethics using ... See more keywords
Clinical Trials of New Drugs for Vascular Cognitive Impairment and Vascular Dementia
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DOI: 10.3390/ijms231911067
Abstract: Population aging has challenged the treatment of cognitive impairment or dementia. Vascular dementia is the second leading cause of dementia after Alzheimer’s disease. Cognitive consequences after ischemic brain injury have been recognized as a preferred… read more here.
Keywords: new drugs; trials new; cognitive impairment; dementia ... See more keywords
Curcumin Formulations and Trials: What’s New in Neurological Diseases
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DOI: 10.3390/molecules25225389
Abstract: Curcumin’s pharmacological properties and its possible benefits for neurological diseases and dementia have been much debated. In vitro experiments show that curcumin modulates several key physiological pathways of importance for neurology. However, in vivo studies… read more here.
Keywords: neurology; trials new; new neurological; neurological diseases ... See more keywords