Analysis of Rates of Completion, Delays, and Participant Recruitment in Randomized Clinical Trials in Surgery
Sign Up to like & getrecommendations! Published in 2023 at "JAMA Network Open"
DOI: 10.1001/jamanetworkopen.2022.50996
Abstract: Key Points Question What are the rates of delays and incomplete enrollment among randomized clinical trials in surgery? Findings In this cross-sectional study of 2542 randomized clinical trials registered on ClinicalTrials.gov between 2010 and 2014,… read more here.
Keywords: trials surgery; clinical trials; completion delays; analysis rates ... See more keywords
Practical Guide to Statistical Considerations in Clinical Trials in Surgery.
Sign Up to like & getrecommendations! Published in 2022 at "JAMA surgery"
DOI: 10.1001/jamasurg.2022.4892
Abstract: This Guide to Statistics and Methods discusses key statistical considerations in the conduct of randomized clinical trials in surgery. read more here.
Keywords: trials surgery; clinical trials; statistical considerations; practical guide ... See more keywords
Reporting of key methodological issues in placebo-controlled trials of surgery needs improvement: a systematic review
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Clinical Epidemiology"
DOI: 10.1016/j.jclinepi.2019.11.016
Abstract: Objectives To examine key methodological considerations for using a placebo intervention in randomized controlled trials (RCTs) evaluating invasive procedures, including surgery. Study Design and Setting RCTs comparing an invasive procedure with a placebo were included… read more here.
Keywords: controlled trials; key methodological; placebo controlled; systematic review ... See more keywords
Delivering successful randomized controlled trials in surgery: Methods to optimize collaboration and study design
Sign Up to like & getrecommendations! Published in 2017 at "Clinical Trials"
DOI: 10.1177/1740774516687272
Abstract: Randomized controlled trials in surgery are notoriously difficult to design and conduct due to numerous methodological and cultural challenges. Over the last 5 years, several UK-based surgical trial-related initiatives have been funded to address these issues.… read more here.
Keywords: randomized controlled; delivering successful; trials surgery; controlled trials ... See more keywords