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Published in 2019 at "Bioorganic chemistry"
DOI: 10.1016/j.bioorg.2019.03.063
Abstract: s-Triazine is considered a privileged structure, as it is found in several FDA-approved drugs. In the framework of our ongoing medicinal chemistry project based on the use of s-triazine as a scaffold, we synthesized a…
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Keywords:
pyrazolyl triazine;
chemistry;
cancer;
triazine derivatives ... See more keywords
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Published in 2021 at "Computational and Theoretical Chemistry"
DOI: 10.1016/j.comptc.2021.113160
Abstract: Abstract We have proposed the structures of three 1,3,5-triazine-2,4-diamine analogs and subjected them to density functional theory (DFT) calculations and molecular dynamics (MD) simulations to assess their potential for applications in the area of organic…
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Keywords:
newly designed;
properties newly;
acridone moieties;
triazine derivatives ... See more keywords
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Published in 2021 at "Journal of Fluorine Chemistry"
DOI: 10.1016/j.jfluchem.2021.109880
Abstract: ABSTRACT A monolayer on the water surface or a Langmuir monolayer of fluorinated long-chain s-triazine derivatives with no hydrophilic groups was formed, and its interfacial conformation was verified. As a highly water-repellent monolayer-forming substance, s-triazine…
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Keywords:
water surface;
water;
monolayer;
hydrophilic groups ... See more keywords
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Published in 2017 at "Journal of Molecular Structure"
DOI: 10.1016/j.molstruc.2017.05.040
Abstract: Abstract A new series of pyrazole-containing s-triazine derivatives were synthesized by reaction of the corresponding s-triazinyl hydrazine derivatives with acetylacetone in the presence of HClO 4 or DMF/TEA. The former method allowed the preparation of…
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Keywords:
pyrazolyl triazine;
molecular structure;
novel pyrazolyl;
triazine derivatives ... See more keywords
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Published in 2017 at "Tribology International"
DOI: 10.1016/j.triboint.2016.12.038
Abstract: Two triazine derivatives, 6-(diethanolamino)−2,4-bi-(sodium sulfanilate-yl)−1,3,5-triazine (STB) and 6-(ethyl xanthate)−2,4-bi-(sodium sulfanilate-yl)−1,3,5-triazine (STC) were synthesized and used as additives in water-glycol base fluid (mass ratio 1:1). Water solubility tests indicated that STB and STC met the solubility…
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Keywords:
water glycol;
sulfur;
water;
stb stc ... See more keywords
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Published in 2020 at "Journal of Physical Chemistry C"
DOI: 10.1021/acs.jpcc.0c08812
Abstract: The peculiar electronic and optical properties of covalent organic frameworks (COFs) are largely determined by protonation, a ubiquitous phenomenon in the solution environment in which they are synthesized. The resulting effects are non-trivial and appear…
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Keywords:
protonated triazine;
properties protonated;
optical properties;
electronic optical ... See more keywords
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Published in 2019 at "Organic letters"
DOI: 10.1021/acs.orglett.9b04335
Abstract: Direct synthesis of N2-substituted triazole and triazine derivatives has been a challenge in N-heterocyclic chemistry. Under copper(II) catalysis ketene N,S-acetals, that is, alkylthio-substituted enaminones, efficiently reacted with aryldiazonium salts to allow the regioselective generation of…
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Keywords:
aryldiazonium salts;
triazole triazine;
substituted triazole;
triazine derivatives ... See more keywords
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Published in 2018 at "ACS applied materials & interfaces"
DOI: 10.1021/acsami.7b18723
Abstract: Chiral amphiphilic oxacalix[2]arene[2]triazine derivatives 1-3 bearing l-prolinol moieties were synthesized. The self-assembly behavior of the chiral macrocyclic amphiphiles was investigated. SEM, TEM, and DLS measurements demonstrated that 1 formed stable vesicles (size of ∼90 nm),…
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Keywords:
amphiphilic oxacalix;
chiral amphiphilic;
arene triazine;
triazine derivatives ... See more keywords
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Published in 2023 at "ACS medicinal chemistry letters"
DOI: 10.1021/acsmedchemlett.3c00122
Abstract: Provided herein are 1,2,4-triazine derivatives used as NLRP3 inhibitors, their pharmaceutical compositions, the use of such compounds in treating diseases and processes for preparing such compounds.
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Keywords:
treating diseases;
chemistry;
derivatives nlrp3;
inhibitors treating ... See more keywords
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Published in 2022 at "ACS Omega"
DOI: 10.1021/acsomega.2c03079
Abstract: Here, we synthesized a newseries of mono- and bis(dimethylpyrazolyl)-s-triazine derivatives. The synthetic methodology involved the reaction of different mono- and dihydrazinyl-s-triazine derivatives with acetylacetone in the presence of triethylamine to produce the corresponding target products…
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Keywords:
dimethylpyrazolyl triazine;
bis dimethylpyrazolyl;
triazine;
activity ... See more keywords
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Published in 2023 at "ACS Omega"
DOI: 10.1021/acsomega.3c01273
Abstract: The biological benefits of trisubstituted 1,3,5-triazine derivatives include their ability to reduce inflammation and fight cancer. A unique series of sulfonamide–triazine hybrid molecules were produced chemically by synthesizing triazine derivatives utilizing the usual nucleophilic aromatic…
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Keywords:
triazine hybrid;
evaluation anticancer;
triazine derivatives;
sulfonamide triazine ... See more keywords