Design, synthesis, and biological evaluation of 4-(1H-1,2,3-triazol-1-yl)benzamides as HSP90 inhibitors.
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DOI: 10.1007/s11030-022-10423-7
Abstract: Heat shock protein 90 (HSP90) is a promising anticancer drug target, which could be employed to construct HSP90 inhibitors-based drug conjugates for selective tumor therapy. Herein, a series of 4-(1H-1,2,3-triazol-1-yl)benzamides were rationally designed, synthesized as… read more here.
Keywords: synthesis biological; hsp90; design synthesis; triazol benzamides ... See more keywords