Metal-free 1,3-dipolar cyclization of azides with HFO-1233zd(E) under amine participation: one-step regioselective synthesis of 1-N-substituted 1,2,3-triazole-4-carboxamide derivatives
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DOI: 10.1039/d3qo00333g
Abstract: A simple and metal-free strategy for regioselective synthesis of 1-N-substituted 1,2,3-triazole-4-carboxamide derivatives was developed by employing azides, HFO-1233zd (E) and amines in aqueous reaction medium. The defluorination functionalization of the... read more here.
Keywords: triazole carboxamide; substituted triazole; metal free; synthesis substituted ... See more keywords