Synthesis and Evaluation of the Antileishmanial Activity of Novel Eugenol Analogs Containing 1,2,3-Triazole Fragments Against Intracellular Leishmania braziliensis
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DOI: 10.21577/0103-5053.20230073
Abstract: This investigation describes the synthesis of eugenol analogs presenting 1,2,3-triazole fragments and evaluation of their antileishmanial activity. The alkylation of guaiacol (1) with allyl bromide afforded 1-(allyloxy)-2-methoxybenzene (2) (93% yield). The Claisen rearrangement conducted with… read more here.
Keywords: braziliensis; evaluation antileishmanial; triazole fragments; eugenol analogs ... See more keywords