Synthesis and inhibitory activity against MurA and MurZ enzymes of 4H-pyrano[2,3-d]pyrimidine−1H-1,2,3-triazole hybrid compounds having piperidine and morpholine rings
Sign Up to like & getrecommendations! Published in 2023 at "New Journal of Chemistry"
DOI: 10.1039/d3nj01718d
Abstract: A series of D-glucose-conjugated 4H-pyrano[2,3-d]pyrimidine−1H-1,2,3-triazole hybrid compounds 12a-g & 13a-g having piperidine and morpholine rings were synthesized by click chemistry between corresponding propargyl derivatives and azide of D-glucose using CuI@Montmorillonite... read more here.
Keywords: piperidine morpholine; chemistry; pyrimidine triazole; hybrid compounds ... See more keywords
Coumarin-1,2,3-triazole hybrid derivatives: Green synthesis and DFT calculations
Sign Up to like & getrecommendations! Published in 2019 at "Synthetic Communications"
DOI: 10.1080/00397911.2018.1557686
Abstract: Abstract A series of new 1,2,3-triazole-coumarin hybrid system are synthesized from the click reaction between 3-azido coumarin and different aromatic terminal alkyne derivatives in a green manner. All compounds are characterized by IR, NMR and… read more here.
Keywords: coumarin triazole; derivatives green; green synthesis; hybrid derivatives ... See more keywords
Facile Synthesis of Novel Isoflavone/1,2,3-Triazole Hybrid Heterocycles as Potential Antimicrobial Agents
Sign Up to like & getrecommendations! Published in 2020 at "Russian Journal of General Chemistry"
DOI: 10.1134/s1070363220050266
Abstract: Abstract A variety of new hybrid derivatives of isoflavone-1,2,3-triazole conjugated heterocycles has been synthesized from 7-hydroxy isoflavone by Cu(I) catalysed azidoalkyne [3+2]cycloaddition. The synthesized compounds have been tested for anti-bacterial activity against gram positive Bacillus… read more here.
Keywords: isoflavone triazole; facile synthesis; isoflavone; synthesis novel ... See more keywords
A Triazole Hybrid of Neolignans as a Potential Antileishmanial Agent by Triggering Mitochondrial Dysfunction.
Sign Up to like & getrecommendations! Published in 2019 at "Molecules"
DOI: 10.3390/molecules25010037
Abstract: In the search for new compounds with antileishmanial activity, we synthesized a triazole hybrid analogue of the neolignans grandisin and machilin G (LASQUIM 25), which was previously found highly active against both promastigotes and intracellular… read more here.
Keywords: hybrid neolignans; antileishmanial agent; neolignans potential; potential antileishmanial ... See more keywords