Triazole-Peptide Conjugate as a Modulator of Aβ-Aggregation, Metal-Mediated Aβ-Aggregation, and Cytotoxicity.
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DOI: 10.1021/acschemneuro.3c00041
Abstract: Amyloid-β (Aβ) aggregation plays a key role in the pathogenesis of Alzheimer's disease (AD). Along with this, the presence of redox-active metals like Cu2+ further enhances Aβ aggregation, oxidative stress, and cellular toxicity. In this… read more here.
Keywords: triazole peptide; aggregation; metal mediated; ds2 ... See more keywords