Triazole resistance in Aspergillus fumigatus exposed to new chiral fungicide mefentrifluconazole.
Sign Up to like & getrecommendations! Published in 2022 at "Pest management science"
DOI: 10.1002/ps.7224
Abstract: BACKGROUND Triazole resistance in human fungal pathogen Aspergillus fumigatus has been a growing challenge in clinic treatment with triazole drugs such as itraconazole. The fast evolvement of triazole-resistance in Aspergillus fumigatus in the ecosystem has… read more here.
Keywords: resistance fumigatus; aspergillus fumigatus; resistance; triazole resistance ... See more keywords
Triazole resistance in Aspergillus fumigatus isolates in Africa: a systematic review.
Sign Up to like & getrecommendations! Published in 2022 at "Medical mycology"
DOI: 10.1093/mmy/myac059
Abstract: Emergence of triazole resistance has been observed in Aspergillus fumigatus over the past decade including in Africa. This review summarizes the current published data on the epidemiology and reported mechanisms of triazole-resistant Aspergillus fumigatus (TRAF)… read more here.
Keywords: aspergillus fumigatus; environmental clinical; resistance; triazole resistance ... See more keywords
hapE and hmg1 Mutations Are Drivers of cyp51A-Independent Pan-Triazole Resistance in an Aspergillus fumigatus Clinical Isolate
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DOI: 10.1128/spectrum.05188-22
Abstract: Triazole resistance is an important cause of treatment failure and high mortality rates for A. fumigatus human infections. Although Cyp51A-associated mutations are frequently identified as the cause of A. fumigatus triazole resistance, they do not… read more here.
Keywords: clinical isolate; hape hmg1; resistance; triazole resistance ... See more keywords
Efficient Generation of Multiple Seamless Point Mutations Conferring Triazole Resistance in Aspergillus fumigatus
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Fungi"
DOI: 10.3390/jof9060644
Abstract: Aspergillus fumigatus is a common human fungal pathogen that can cause a range of diseases. Triazoles are used to treat A. fumigatus infections, but resistance is increasing due to mutations in genes such as cyp51A,… read more here.
Keywords: conferring triazole; efficient generation; aspergillus fumigatus; mutations conferring ... See more keywords