Synthesis and Immunological Evaluation of Mannosylated Desmuramyl Dipeptides Modified by Lipophilic Triazole Substituents
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DOI: 10.3390/ijms23158628
Abstract: Muramyl dipeptide (N-acetylmuramyl-L-alanyl-D-isoglutamine, MDP) is the smallest peptidoglycan fragment able to trigger an immune response by activating the NOD2 receptor. Structural modification of MDP can lead to analogues with improved immunostimulating properties. The aim of… read more here.
Keywords: lipophilic triazole; evaluation mannosylated; immunological evaluation; synthesis immunological ... See more keywords