METHODS OF SYNTHESIS OF [1,2,4]TRIAZOLO[1,5- а ]PYRIDINES
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DOI: 10.1007/5075
Abstract: В микрообзоре обобщены данные по новым методам синтеза [1,2,4]триазоло[1,5-а]пиридинов, опубликованные начиная с 2002 г. Методы классифицированы по типам используемых реагентов. read more here.
Keywords: methods synthesis; triazolo pyridines; chemistry; synthesis triazolo ... See more keywords
AN EFFICIENT METHOD FOR ACCESSING CARBOANNULATED AND FUNCTIONALIZED [1,2,3]TRIAZOLO[4,5- b ]PYRIDINES
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DOI: 10.1007/5653
Abstract: 4-(N-Boc-amino)-1,2,3-triazole-5-carbaldehydes upon heating under reflux in acetic acid in the presence of pyrrolidine react with cycloalkanones, acetylacetone, 1,3-cyclohexanediones, and malononitrile resulting in annulation of the pyridine ring with the formation of new derivatives of [1,2,3]triazolo[4,5-b]pyridine. read more here.
Keywords: efficient method; carboannulated functionalized; triazolo pyridines; method accessing ... See more keywords
Synthesis of pyrano[3,4-c]thieno[3,2-e][1,2,4]triazolo[4,3-a]pyridines, representatives of a new fused heterocyclic system
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DOI: 10.1016/j.mencom.2020.03.017
Abstract: New effective synthesis of functionalized pyrano[3,4-c]thieno-[3,2-e][1,2,4]triazolo[4,3-a]pyridines comprises nucleophilic substitution in 8-morpholino-6-thioxopyrano[3,4-c]pyridine-5-carbonitrile with hydrazine hydrate followed by sequential heterocyclization with formic acid and chloroacetic acid derivatives. read more here.
Keywords: synthesis; thieno triazolo; triazolo pyridines; pyrano thieno ... See more keywords
The Diverse supramolecular synthons formed by 2-subsituted 5-morpholinomethylphenyl Triazolo[1,5-a]pyridines in solid state
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Molecular Structure"
DOI: 10.1016/j.molstruc.2018.08.088
Abstract: Abstract 1,2,4-Triazolo[1,5-a]pyridines emerge as promising pharmacophores whose properties depend critically on 2- and 5-positioned substituents. We synthesized three new 1,2,4-triazolo[1,5-a]pyridine derivatives with different 2-substituents in combination with a morpholinomethylphenyl group at 5-position. Due to their… read more here.
Keywords: triazolo pyridines; diverse supramolecular; supramolecular synthons; morpholinomethylphenyl ... See more keywords
Access to 3-Amino-[1,2,4]-triazolo Pyridines and Related Heterocycles via Electrochemically Induced Desulfurative Cyclization.
Sign Up to like & getrecommendations! Published in 2022 at "Organic letters"
DOI: 10.1021/acs.orglett.2c01968
Abstract: An efficient, one-pot approach has been established for synthesizing a wide range of 3-amino-[1,2,4]-triazolo pyridines and related heterocycles from the electrochemically induced desulfurative cyclization of 2-hydrazinopyridines with isothiocyanates. The protocol allows for the formation of… read more here.
Keywords: pyridines related; amino triazolo; related heterocycles; triazolo pyridines ... See more keywords
Supramolecular Anion Recognition Mediates One-Pot Synthesis of 3-Amino-[1,2,4]-triazolo Pyridines from Thiosemicarbazides.
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DOI: 10.1021/acs.orglett.6b03645
Abstract: A facile one-pot synthesis of 3-amino-[1,2,4]-triazolo[4,3-a]pyridines from thiosemicarbazides through anion mediated synthesis is reported. Thiosemicarbazides derived from 2-hydrazino pyridine, 5-chloro 2-hydrazino pyridine, and 2-hydrazine quinoline were formed in situ as anion receptors in the presence… read more here.
Keywords: anion; pot synthesis; triazolo pyridines; one pot ... See more keywords