Synthesis and Evaluation of Novel [1,2,4]Triazolo[1,5‐c]quinazoline Derivatives as Antibacterial Agents
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DOI: 10.1002/jhet.2979
Abstract: A series of new 2-aryl-5-methyl-[1,2,4]triazolo[1,5-c]quinazoline derivatives (5a–5g) have been synthesized by the reaction of 3-amino-2-methylquinazolin-4-(3H)-one (3) with aromatic nitriles in potassium tert-butoxide under reflux conditions. 3-Amino-2-methylquinazolin-4-(3H)-one (3) was synthesized by the reaction 2-methyl-4H-benzo[d][1,3]oxazin-4-one (2) with… read more here.
Keywords: triazolo quinazoline; synthesis evaluation; quinazoline derivatives; evaluation novel ... See more keywords