Exploring the pharmacological versatility of triazolopyrazine: A multi-target scaffold for drug development.
Sign Up to like & getrecommendations! Published in 2025 at "Future medicinal chemistry"
DOI: 10.1080/17568919.2025.2580922
Abstract: The triazolopyrazine scaffold is characterized by fused triazole and pyrazine rings. It represents a highly versatile, nitrogen-rich heterocyclic framework extensively explored as a prominent scaffold that is of greater importance for developing novel drugs with… read more here.
Keywords: chemistry; triazolopyrazine; drug; triazolopyrazine scaffold ... See more keywords
Synthesis and characterisation of new antimalarial fluorinated triazolopyrazine compounds
Sign Up to like & getrecommendations! Published in 2023 at "Beilstein Journal of Organic Chemistry"
DOI: 10.3762/bjoc.19.11
Abstract: Nine new fluorinated analogues were synthesised by late-stage functionalisation using Diversinate™ chemistry on the Open Source Malaria (OSM) triazolopyrazine scaffold (Series 4). The structures of all analogues were fully characterised by NMR, UV and MS… read more here.
Keywords: triazolopyrazine; characterisation new; chemistry; synthesis characterisation ... See more keywords