Triazoloquinazoline derived classical DNA intercalators: Design, synthesis, in silico ADME profile, docking, and antiproliferative evaluations
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DOI: 10.1002/ardp.202100506
Abstract: Thirteen novel [1,2,4]triazolo[4,3‐c]quinazoline derivatives as DNA intercalators were synthesized and their anticancer activities evaluated against HepG2 and HCT‐116 cells. A docking study was carried out to explore how the new derivatives bind to active sites… read more here.
Keywords: classical dna; dna; derived classical; triazoloquinazoline derived ... See more keywords