Discovery of Potent, Selective Triazolothiadiazole-Containing c-Met Inhibitors.
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DOI: 10.1021/acsmedchemlett.1c00094
Abstract: Herein, we report a novel series of highly potent and selective triazolothiadiazole c-Met inhibitors. Starting with molecule 5, we have applied structure-based drug design principles to identify the triazolothiadiazole ring system. We successfully replaced the… read more here.
Keywords: potent selective; discovery potent; met inhibitors; triazolothiadiazole containing ... See more keywords