Synthesis of triazolotriazine derivatives as c-Met inhibitors
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DOI: 10.1007/s11030-020-10067-5
Abstract: Receptor tyrosine kinase c-Met is an important antitumor drug target. Triazolotriazine analogues 2–10 were prepared efficiently and evaluated the enzymatic and cellular c-Met activities. Brief structure–activity relationships of triazolotriazine core and CF2-quinoline part were investigated,… read more here.
Keywords: derivatives met; met inhibitors; synthesis triazolotriazine; triazolotriazine derivatives ... See more keywords