Synthesis, antiproliferative activity and DNA/RNA-binding properties of mono- and bis-(1,2,3-triazolyl)-appended benzimidazo[1,2-a]quinoline derivatives.
Sign Up to like & getrecommendations! Published in 2019 at "European journal of medicinal chemistry"
DOI: 10.1016/j.ejmech.2019.111845
Abstract: The three series of 5-mono- and 2,5-bis-1,2,3-triazolyl-substituted benzimidazo[1,2-a]quinolines as potential antitumor agents were synthesized. Their growth-inhibitory activity is influenced by the introduction of fluorine at C-2 and the mono-triazolyl nuclei at C-5 of the tetracyclic… read more here.
Keywords: bis triazolyl; dna; mono bis; rna binding ... See more keywords
Rhodium-catalyzed denitrogenative transannulation of 1,2,3-triazolyl-carbamates: efficient access to 4-aminooxazolidinones
Sign Up to like & getrecommendations! Published in 2017 at "Organic chemistry frontiers"
DOI: 10.1039/c7qo00101k
Abstract: Herein we describe a novel Rh(II)-catalyzed intramolecular transannulation reaction of 1,2,3-triazolyl carbamates to access functionalized 4-aminooxazolidinones under operationally simple conditions with low catalyst loadings. A one-pot tandem Cu(I)-catalyzed synthesis of 1,2,3-triazolyl-carbamates from propargyl carbamates followed… read more here.
Keywords: catalyzed denitrogenative; transannulation; rhodium catalyzed; triazolyl carbamates ... See more keywords
Efficient and simple synthesis of novel 1,2,3-triazolyl-linked benzimidazolone, molecular docking and evaluation of their antimicrobial activity
Sign Up to like & getrecommendations! Published in 2020 at "Synthetic Communications"
DOI: 10.1080/00397911.2020.1803913
Abstract: Abstract In this study, a novel series of 1,2,3-triazolyl-benzimidazolone derivatives have been synthesized by click reaction of azides with benzimidazolones 2a–b. The latter compounds were prepared with excellent yields (85–97%), the structures of products were… read more here.
Keywords: simple synthesis; benzimidazolone; efficient simple; triazolyl ... See more keywords
Synthesis of new p-tert-butylcalix[4]arene-based polyammonium triazolyl amphiphiles and their binding with nucleoside phosphates
Sign Up to like & getrecommendations! Published in 2018 at "Beilstein Journal of Organic Chemistry"
DOI: 10.3762/bjoc.14.173
Abstract: The synthesis of new calix[4]arenes adopting a cone stereoisomeric form bearing two or four azide fragments on the upper rim and water-soluble triazolyl amphiphilic receptors with two or four polyammonium headgroups via copper-catalyzed azide–alkyne cycloaddition… read more here.
Keywords: synthesis new; tert butylcalix; polyammonium; new tert ... See more keywords