Design and synthesis of novel 3-triazolyl-1-thiogalactosides as galectin-1, -3 and -8 inhibitors
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DOI: 10.1039/d2ra03163a
Abstract: Galectins are galactoside-binding proteins that play a role in various pathophysiological conditions, making them attractive targets in drug discovery. We have designed and synthesised a focused library of aromatic 3-triazolyl-1-thiogalactosides targeting their core site for… read more here.
Keywords: design synthesis; synthesis novel; galectin inhibitors; triazolyl thiogalactosides ... See more keywords