Articles with "triazone ensitrelvir" as a keyword



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Small change for big improvement in the preparation of the key intermediate N1, N3-disubstituted 1,3,5-triazone of ensitrelvir

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Published in 2023 at "RSC Advances"

DOI: 10.1039/d2ra07844a

Abstract: In this study, the key intermediate N1, N3-disubstituted 1,3,5-triazone of ensitrelvir fumaric acid, approved in Japan for the treatment of SARS-CoV-2 infection under the emergency regulatory approval system, was produced from S-ethylisothiourea hydrobromide and aminomethyl… read more here.

Keywords: intermediate disubstituted; ensitrelvir; triazone ensitrelvir; disubstituted triazone ... See more keywords