Trib1 promotes acute myeloid leukemia progression by modulating the transcriptional programs of Hoxa9.
Sign Up to like & getrecommendations! Published in 2020 at "Blood"
DOI: 10.1182/blood.2019004586
Abstract: The pseudokinase Trib1 functions as a myeloid oncogene that recruits the E3 ubiquitin ligase COP1 to C/EBPa and interacts with MEK1 to enhance ERK phosphorylation. Close genetic effect of Trib1 on Hoxa9 has been observed… read more here.
Keywords: trib1 promotes; myeloid leukemia; hoxa9; trib1 ... See more keywords