Effects of TLR agonists on immune responses in Trichinella spiralis infected mice
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DOI: 10.1007/s00436-020-06747-8
Abstract: Human trichinellosis is acquired by eating raw or undercooked meats carrying muscle larvae of Trichinella spp. Toll-like receptors (TLRs) are essential components of the innate immune system. However, little is known about the potential application… read more here.
Keywords: tlr agonists; trichinella; trichinella spiralis; spiralis infection ... See more keywords
Prevalence of Trichinella spiralis and Trichinella britovi in wild boars in the northeast of Spain
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DOI: 10.1007/s10344-021-01458-6
Abstract: A total of 33,206 wild boars (Sus scrofa) hunted throughout the province of Girona (northeastern Spain) were submitted to a game processing plant during four hunting seasons (2014–2015 to 2017–2018). This province is divided into… read more here.
Keywords: trichinella; wild boars; trichinella spiralis; trichinella britovi ... See more keywords
Comparative proteomics analysis of Trichinella spiralis muscle larvae exposed to albendazole sulfoxide stress.
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DOI: 10.1016/j.actatropica.2017.12.023
Abstract: The drug albendazole (ABZ) has a positive effect against Trichinella spiralis infection and has been used for the treatment and prevention of trichinellosis in humans and animals. However, the molecular mechanism ofthe effects of ABZ… read more here.
Keywords: albendazole sulfoxide; muscle larvae; analysis; trichinella spiralis ... See more keywords
Binding of elastase-1 and enterocytes facilitates Trichinella spiralis larval intrusion of the host's intestinal epithelium.
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DOI: 10.1016/j.actatropica.2020.105592
Abstract: Elastase-1 is one member of serine protease family, distributes in organisms widely and plays a crucial role in the invasion and development of Trichinella spiralis. In order to identify the binding of T. spiralis elastase-1… read more here.
Keywords: intrusion; host intestinal; larval intrusion; trichinella spiralis ... See more keywords
Chitosan coated nanostructured lipid carriers for enhanced in vivo efficacy of albendazole against Trichinella spiralis.
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DOI: 10.1016/j.carbpol.2019.115826
Abstract: The study investigated chitosan coated nanostructured lipid carriers (NLCs) for oral delivery of albendazole in treatment of trichinellosis. NLCs comprised precirol and oleic acid with Tween and Span 80. Dicetylphosphate was used as charging agent… read more here.
Keywords: nlcs; trichinella spiralis; chitosan coated; coated nanostructured ... See more keywords
Characterization of a putative glutathione S-transferase of the parasitic nematode Trichinella spiralis.
Sign Up to like & getrecommendations! Published in 2018 at "Experimental parasitology"
DOI: 10.1016/j.exppara.2018.02.005
Abstract: The aim of this study was to identify the biological characteristics and functions of a putative Trichinella spiralis glutathione S-transferase (TspGST). The results of real-time PCR and immunofluorescent test (IFT) showed that the TspGST gene… read more here.
Keywords: glutathione transferase; trichinella spiralis; anti rtspgst;
Immunomodulatory effects of Trichinella spiralis excretory-secretory antigens on macrophages.
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DOI: 10.1016/j.exppara.2018.10.001
Abstract: Helminths and their products can suppress the host immune response and other immunopathologies which may benefit parasite survival. Parasitic nematode Trichinella spiralis (T. spiralis) exert immunomodulatory effect on the host immune response through excretory-secretory (ES)… read more here.
Keywords: host immune; excretory secretory; response; trichinella spiralis ... See more keywords
Higher mucosal type II immunity is associated with increased gut microbiota diversity in BALB/c mice after Trichinella spiralis infection.
Sign Up to like & getrecommendations! Published in 2021 at "Molecular immunology"
DOI: 10.1016/j.molimm.2021.07.014
Abstract: Understanding the interaction between the gut microbiota and Trichinella spiralis is of interest for the early diagnosis and development of therapeutics for trichinellosis and to reveal the potential role of microbiota in the mechanism of… read more here.
Keywords: trichinella spiralis; spiralis infection; infection; gut microbiota ... See more keywords
Use of ELISA and Western blot for serological detection of antibodies to E-S antigens of Trichinella spiralis muscle larvae in sera of swine experimentally infected with Trichinella spiralis.
Sign Up to like & getrecommendations! Published in 2018 at "Veterinary immunology and immunopathology"
DOI: 10.1016/j.vetimm.2018.07.010
Abstract: The aim of the present study was to evaluate the detection of trichinellosis using ELISA, and to determine the degree of variation of IgG antibodies against excretory-secretory (E-S) antigens of T. spiralis muscle larvae. Ten… read more here.
Keywords: muscle larvae; trichinella; spiralis; trichinella spiralis ... See more keywords
Trichinella spiralis prevalence among wildlife of a boreal region rapidly reduced in the absence of spillover from the domestic cycle.
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DOI: 10.1016/j.vetpar.2018.09.002
Abstract: Carnivore and omnivore animals are the main reservoir hosts of nematodes of the genus Trichinella. Out of the twelve taxa identified so far in the world, four, namely Trichinella spiralis, Trichinella nativa, Trichinella britovi and… read more here.
Keywords: trichinella; trichinella spiralis; domestic cycle; prevalence ... See more keywords
Functional characterization of a glutathione S-transferase in Trichinella spiralis invasion, development and reproduction.
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DOI: 10.1016/j.vetpar.2020.109128
Abstract: The purpose of this study was to determine the biological function of a Trichinella spiralis glutathione S-transferase (TsGST) in larval invasion and development by RNA interference (RNAi). The TsGST-specific siRNA 366 was transfected into T.… read more here.
Keywords: tsgst; trichinella; trichinella spiralis; invasion development ... See more keywords