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Published in 2024 at "Protein Science"
DOI: 10.1002/pro.5225
Abstract: The protozoan parasite Trichomonas vaginalis (Tv) causes trichomoniasis, the most common non‐viral sexually transmitted infection in the world. Although Tv has been linked to significant health complications, only two closely related 5‐nitroimidazole drugs are approved…
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Keywords:
distinct substrate;
substrate specificities;
trichomonas vaginalis;
catalytic subunits ... See more keywords
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Published in 2022 at "Veterinary Medicine and Science"
DOI: 10.1002/vms3.977
Abstract: Abstract Background Trichomonas vaginalis is a protist parasite that causes trichomoniasis, a sexually transmitted disease. Metronidazole is the current treatment for trichomoniasis. However, this drug can provoke severe side effects, and some strains present resistance,…
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Keywords:
apoptosis;
oil;
essential oil;
kotschyi ... See more keywords
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Published in 2021 at "Parasitology Research"
DOI: 10.1007/s00436-021-07177-w
Abstract: Reports on metronidazole resistance of Trichomonas vaginalis strains have been on the increase. This study investigated the in vitro metronidazole resistance patterns in T. vaginalis isolates obtained from South African pregnant women and the genotypes…
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Keywords:
susceptibility patterns;
metronidazole susceptibility;
susceptibility;
pregnant women ... See more keywords
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Published in 2021 at "Parasitology research"
DOI: 10.1007/s00436-021-07216-6
Abstract: Trichomoniasis is a sexually transmitted infection (STI), caused by the protozoan parasite, Trichomonas vaginalis. Female sex workers are intensely affected by the infection, since they have frequent direct physical contact. The current systematic review and…
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Keywords:
trichomonas vaginalis;
systematic review;
prevalence;
female sex ... See more keywords
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Published in 2025 at "Parasitology Research"
DOI: 10.1007/s00436-025-08463-7
Abstract: Trichomonas vaginalis infections significantly impact public health and are associated with increased likelihood of HIV infection, prostate cancer, and pregnancy complications. Current treatment relies almost exclusively on 5-nitroimidazoles, particularly metronidazole, raising concerns about drug resistance…
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Keywords:
resistance;
efflux pump;
trichomonas vaginalis;
metronidazole resistant ... See more keywords
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Published in 2017 at "BioMetals"
DOI: 10.1007/s10534-017-0053-7
Abstract: The zinc fingers proteins (ZNF) are the largest family of DNA binding proteins and can act as transcriptional factors in eukaryotes. ZNF are implicated in activation in response to environmental stimulus by biometals such as…
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Keywords:
tvznf1;
zinc;
zinc finger;
trichomonas vaginalis ... See more keywords
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Published in 2021 at "Contraception"
DOI: 10.1016/j.contraception.2021.01.011
Abstract: INTRODUCTION The Centers for Disease Control and Prevention (CDC) recommend considering screening asymptomatic women for trichomonas in high-prevalence settings. Whether urban abortion clinics constitute such a setting is unknown. MATERIAL AND METHODS We offered trichomonas…
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Keywords:
abortion;
patients presenting;
offering universal;
presenting abortion ... See more keywords
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Published in 2017 at "Microbes and infection"
DOI: 10.1016/j.micinf.2016.11.001
Abstract: Trichomonas vaginalis causes the most common non-viral sexually transmitted disease worldwide. The cytoadherence and cytotoxicity upon the vaginal epithelial cells are crucial for the infection. Extracellular nucleotides are released during cell damage and, along with…
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Keywords:
epithelial cells;
vaginalis cytotoxicity;
vaginal epithelial;
guanosine ... See more keywords
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Published in 2017 at "Microbial pathogenesis"
DOI: 10.1016/j.micpath.2017.04.032
Abstract: The Totiviridae family includes a number of viruses that can infect protozoan parasites such as Leishmania and Giardia and fungi like Saccharomyces cerevisiae. Some isolates of Trichomonas vaginalis are also infected with one or more…
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Keywords:
iranian isolates;
infection;
double stranded;
tvv1 ... See more keywords
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Published in 2021 at "Microbial pathogenesis"
DOI: 10.1016/j.micpath.2021.105058
Abstract: BACKGROUND The small (4.5-5kbp), double-stranded Trichomonas vaginalis virus (TVV) that inhabits in the T. vaginalis parasite has been potentially associated to parasite virulence or its drug resistance. The aim of present study was to estimate…
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Keywords:
prevalence;
trichomonas;
trichomonas vaginalis;
virus ... See more keywords
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Published in 2019 at "Molecular and biochemical parasitology"
DOI: 10.1016/j.molbiopara.2018.12.004
Abstract: The parasitic protozoon Trichomonas vaginalis is the pathogen of trichomoniasis, the most common non-viral, sexually transmitted disease in humans. Inositol phosphates function in the pathomechanisms of a number of human pathogenic protozoa. Recent findings point…
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Keywords:
protozoon trichomonas;
kinase;
novel pyrophosphorylating;
trichomonas vaginalis ... See more keywords