Antiplasmodial Sesquiterpenoid Lactones from Trichospira verticillata: Structure Elucidation by Spectroscopic Methods and Comparison of Experimental and Calculated ECD Data.
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DOI: 10.1021/acs.jnatprod.7b00247
Abstract: A dichloromethane extract of Trichospira verticillata from the Natural Products Discovery Institute was discovered to have good antiplasmodial activity (IC50 ∼5 μg/mL). After purification by liquid-liquid partition and C18 reversed-phase HPLC, four new germacranolide-type sesquiterpenoid… read more here.
Keywords: sesquiterpenoid lactones; lactones trichospira; ecd; verticillata structure ... See more keywords