Resistance-driven innovations in the discovery of bactericides: novel triclosan derivatives decorating isopropanolamine moiety as promising anti-biofilm agents against destructive plant bacterial diseases.
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DOI: 10.1002/ps.7419
Abstract: BACKGROUND Controlling bacterial infections in plants is a major challenge due to the appearance of resistant strains. As a physical barrier, the bacterial biofilm helps bacterial infections acquire drug resistance by enabling bacteria to accommodate… read more here.
Keywords: bacterial diseases; plant bacterial; biofilm; resistance ... See more keywords
Triclosan and its derivatives as antimycobacterial active agents
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DOI: 10.1016/j.ejps.2017.12.013
Abstract: Abstract Tuberculosis (TB) represents one of the leading causes of morbidity and mortality worldwide. Development of new potential drugs is essential because of the existence of latent TB and expansion of drug‐resistant TB forms (multidrug‐resistant… read more here.
Keywords: active agents; derivatives antimycobacterial; tuberculosis; triclosan derivatives ... See more keywords
Theoretical design of novel antimalarial agents against P. falciparum strain, Dd2 through the QSAR modeling of synthesized 2′-substituted triclosan derivatives
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DOI: 10.1016/j.heliyon.2020.e05032
Abstract: In an attempt to design compounds with higher antimalarial activities, quantitative structure-activity relationship (QSAR) technique was utilized in the development of a molecular model for some synthesized 2′-substituted triclosan derivatives through a hybrid of the… read more here.
Keywords: substituted triclosan; qsar; synthesized substituted; triclosan derivatives ... See more keywords