Inhibitory Effect of Tricyclic Antidepressant Doxepin on Voltage-Dependent K+ Channels in Rabbit Coronary Arterial Smooth Muscle Cells
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DOI: 10.1007/s12012-019-09519-8
Abstract: Doxepin, tricyclic antidepressant, is widely used for the treatment of depressive disorders. Our present study determined the inhibitory effect of doxepin on voltage-dependent K+ (Kv) channels in freshly isolated rabbit coronary arterial smooth muscle cells… read more here.
Keywords: doxepin; tricyclic antidepressant; voltage dependent; inhibitory effect ... See more keywords
Theoretical and spectroscopic studies of a tricyclic antidepressant, imipramine hydrochloride
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DOI: 10.1016/j.molstruc.2018.02.056
Abstract: Abstract Imipramine hydrochloride ([H-IMI]Cl), C19H24N2.HCl, is the prototypic tricyclic antidepressant (TCA) inhibitor of norepinephrine and serotonin neuronal reuptake. The molecular structure, molecular electrostatic potential (MEP), natural bond orbital (NBO) analysis, linear and non-linear optical (NLO)… read more here.
Keywords: analysis; imipramine hydrochloride; tricyclic antidepressant; theoretical spectroscopic ... See more keywords
Inhibitory effect of the tricyclic antidepressant amitriptyline on voltage‐dependent K+ channels in rabbit coronary arterial smooth muscle cells
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DOI: 10.1111/1440-1681.12857
Abstract: Amitriptyline, a tricyclic antidepressant (TCA) drug, is widely used in treatment of psychiatric disorders. However, the side effects of amitriptyline on vascular K+ channels remain to be determined. Therefore, we investigated the effect of the… read more here.
Keywords: amitriptyline voltage; effect tricyclic; effect; tricyclic antidepressant ... See more keywords