Articles with "tricyclic cage" as a keyword



New tricyclic cage compound as allosteric modulator of the glutamatergic system: synthesis and biological activity

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Published in 2025 at "Mendeleev Communications"

DOI: 10.71267/mencom.7654

Abstract: A new tricyclic derivative of 1,5-dimethyl-3,7-diazabicyclo[3.3.1]nonane was synthesized in three steps using 2-aminoindane-5-carbonitrile. A positive modulatory activity of this compound towards the glutamatergic system in a wide range of nanomolar and subnanomolar concentrations has been… read more here.

Keywords: compound; glutamatergic system; new tricyclic; tricyclic cage ... See more keywords