Identification of good and bad fragments of tricyclic triazinone analogues as potential PKC-θ inhibitors through SMILES–based QSAR and molecular docking
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DOI: 10.1007/s11224-020-01629-2
Abstract: Based on the mechanism of action of PKC-θ, the inhibition of this enzyme is considered a potential target for the treatment of autoimmune diseases such as rheumatoid arthritis (RA), inflammatory bowel disease (IBD), and psoriasis.… read more here.
Keywords: potential pkc; triazinone analogues; pkc inhibitors; pkc ... See more keywords